Dendritic cells (DCs) are stalwarts of the immune response, activating both the innate and acquired immune systems. In the October 26 Science Qian Huang and colleagues at the Whitehead Institute for Biomedical Research describe the use of oligonucleotide microarrays to examine how DCs respond to different pathogens (Science 2001, 294:870-875).They exposed human monocyte-derived DCs to Gram-negative bacteria (Escherichia coli), fungi (Candida albicans) or an RNA virus (influenza virus), and then
Dendritic cells (DCs) are stalwarts of the immune response, activating both the innate and acquired immune systems. In the October 26
They exposed human monocyte-derived DCs to Gram-negative bacteria (
Huang et al. also noted early changes in genes involved in phagocytosis, cytokine production and the cytoskeleton composition. Later phases were accompanied by changes in signalling genes, transcription factors ...
The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.
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