Diabetes Is Five Diseases, Not Two

The new classification system could help improve personalized medicine approaches to the disease.

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ISTOCK, ANDREY POPOV

Diabetes is a group of five diseases with distinct genetic and physiological profiles, according to a study published in The Lancet Diabetes & Endocrinology last week (March 1).

Traditionally, diabetes—a condition that affects more than 100 million Americans—has had just two classifications. However, clinicians were aware that type 1 and type 2 was “not a terribly accurate classification system” for the disease, Victoria Salem, a clinical scientist at Imperial College London who was not involved in the study, tells the BBC.

To identify more refined categories, researchers at the Lund University Diabetes Centre in Sweden and the Institute for Molecular Medicine in Finland analyzed the medical records and blood of 14,775 patients. They examined various diabetes-related measurements, such as long-term glycemic control, insulin resistance, and ...

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