Big data and empirical approaches to understanding diseases provide a limited picture of pathogenesis.

Scientists engineered human cells to produce a molecule that stimulates insulin secretion in the presence of caffeine.

Low levels of a biochemical process involved in fat breakdown predicts weight gain and metabolic complications more than a decade later.

One patient with diabetes was able to reduce his medication use while receiving targeted electrical pulses.

Researchers used a trio of transcription factors to transform pancreatic duct cells in vivo into β-like cells that secrete insulin and improve diabetes symptoms.

A new study reports that immune memory may contribute to neurodegenerative diseases.

A study of more than 450,000 people finds a certain genetic variant associated with eating more carbs is linked to a thicker waist and higher blood pressure, but less fat.  

New findings suggest that promoting the growth of fiber-loving bacteria may help manage type 2 diabetes.

The new classification system could help improve personalized medicine approaches to the disease.