Drug Development Could Suffer from Proposed NIH Budget Cuts

An analysis of President Trump’s proposed $7.2 billion slash to the National Institutes of Health budget points to dire consequences for the development of novel drugs.

Written byJef Akst
| 2 min read

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FLICKR, CHRIS POTTERIn March, President Donald Trump’s administration released its proposed 2018 budget, which included a significant cut to funding for the National Institutes of Health (NIH). Now, an analysis from researchers at Washington University School of Medicine in St. Louis suggests that the reduction—which amounts to $7.2 billion, or 21 percent of the agency’s bolstered 2017 budget—could hamper researchers’ ability to develop novel, potentially life-saving drugs.

That conclusion was reached by looking at how NIH and US Food and Drug Administration (FDA) budgets have affected drug development in the past. The researchers found that the vast majority of new drugs were supported by NIH funding early in development. The results were published this week (November 16) in Cell Chemical Biology.

Specifically, the new analysis found that 93 of the 100 most commonly prescribed drugs in the U.S. had relied on NIH support. Looking at all new drugs approved by the FDA between 2010 and 2016, the researchers calculated that 97 percent had received NIH funding at some point during their development.

“NIH funding is instrumental in the early research needed to develop FDA-approved medicines,” coauthor Michael Kinch, an associate vice chancellor ...

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  • Jef (an unusual nickname for Jennifer) got her master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses. After four years of diving off the Gulf Coast of Tampa and performing behavioral experiments at the Tennessee Aquarium in Chattanooga, she left research to pursue a career in science writing. As The Scientist's managing editor, Jef edited features and oversaw the production of the TS Digest and quarterly print magazine. In 2022, her feature on uterus transplantation earned first place in the trade category of the Awards for Excellence in Health Care Journalism. She is a member of the National Association of Science Writers.

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