Drug Development Could Suffer from Proposed NIH Budget Cuts

An analysis of President Trump’s proposed $7.2 billion slash to the National Institutes of Health budget points to dire consequences for the development of novel drugs.

Written byJef Akst
| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

FLICKR, CHRIS POTTERIn March, President Donald Trump’s administration released its proposed 2018 budget, which included a significant cut to funding for the National Institutes of Health (NIH). Now, an analysis from researchers at Washington University School of Medicine in St. Louis suggests that the reduction—which amounts to $7.2 billion, or 21 percent of the agency’s bolstered 2017 budget—could hamper researchers’ ability to develop novel, potentially life-saving drugs.

That conclusion was reached by looking at how NIH and US Food and Drug Administration (FDA) budgets have affected drug development in the past. The researchers found that the vast majority of new drugs were supported by NIH funding early in development. The results were published this week (November 16) in Cell Chemical Biology.

Specifically, the new analysis found that 93 of the 100 most commonly prescribed drugs in the U.S. had relied on NIH support. Looking at all new drugs approved by the FDA between 2010 and 2016, the researchers calculated that 97 percent had received NIH funding at some point during their development.

“NIH funding is instrumental in the early research needed to develop FDA-approved medicines,” coauthor Michael Kinch, an associate vice chancellor ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

  • Jef (an unusual nickname for Jennifer) got her master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses. After four years of diving off the Gulf Coast of Tampa and performing behavioral experiments at the Tennessee Aquarium in Chattanooga, she left research to pursue a career in science writing. As The Scientist's managing editor, Jef edited features and oversaw the production of the TS Digest and quarterly print magazine. In 2022, her feature on uterus transplantation earned first place in the trade category of the Awards for Excellence in Health Care Journalism. She is a member of the National Association of Science Writers.

    View Full Profile
Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies