Two genes have been found to down-regulate the non-homologous end-joining pathway in meiotic diploid yeast cells.
The DNA-repair mechanism referred to as non-homologous end-joining (NHEJ) involves the Ku proteins (Ku70 and Ku80), DNA ligase IV and Lif1/XRCC4. Meiotic cells down-regulate NHEJ, to favour homologous recombination. In the December 6
They found that
Valencia et al. suggest that NEJ1 affects the cellular localization of LIF1 during meoisis. It will be interesting to see whether similar regulation of NHEJ components occurs during ...
These fluttering sensations are the brain’s reaction to certain emotions, which can be amplified or soothed by the gut’s own “bugs".
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Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.
In our next roundtable webinar, learn how scientists leverage spatial biology to map tissues, uncover cellular interactions, and advance disease research.
Discover how scientists use the latest gene editing tools to advance health research.
Ten-year Agreement to Provide a Secure, AI-enabled Forensic Laboratory Information Management System Supporting DHS Forensic, Scientific, and Testing Services
deliver robust, reproducible solutions for sample preparation enabling a new era of end-to-end standardization in proteomics
Enables higher-throughput, cost effective single-cell sequencing
Enables ultra-low variant detection across a range of key MRD targets in AML, including very large FLT3-ITDs
