Fighting Fire with Fire

Exposing severly allergic children to progressively larger amounts of peanut flour desensitizes them over time, a study shows.

kerry grens
| 2 min read

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WIKIMEDIA, ALICE WELCHIt’s a frightening thought: deliberately feeding peanut protein to severely allergic children. But that approach has actually fought back children’s allergic reactions, according to results from a study published in The Lancet today (January 30). “We’ve shown fantastic results, with 80 [percent] to 90 percent of children being able to tolerate eating peanuts regularly after treatment,” lead researcher Andrew Clark of Addenbrooke’s Hospital in Cambridge, UK, told New Scientist.

Clark and his colleagues fed several dozen kids peanut flour in tiny amounts—just 2 milligrams (mg) to begin with—and gradually increased the daily dose to 800 mg over a course of six months. By the end of the study, 84 percent of participants could safely eat several peanuts’ worth of the protein at a time. “It’s huge, absolutely huge,” Maureen Jenkins, the director of clinical services at Allergy UK, told New Scientist. “There hasn’t been any way of treating this before.”

The scientists caution that this should not be used as a home remedy to treat peanut allergy, and said that it’s too soon to know whether the approach will work outside of a research setting. There were many more allergic events among the kids ...

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  • kerry grens

    Kerry Grens

    Kerry served as The Scientist’s news director until 2021. Before joining The Scientist in 2013, she was a stringer for Reuters Health, the senior health and science reporter at WHYY in Philadelphia, and the health and science reporter at New Hampshire Public Radio. Kerry got her start in journalism as a AAAS Mass Media fellow at KUNC in Colorado. She has a master’s in biological sciences from Stanford University and a biology degree from Loyola University Chicago.

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