Natural Killer Cell Therapies Catch Up to CAR T
Natural Killer Cell Therapies Catch Up to CAR T
There’s a new cell-based cancer immunotherapy on the block.
Natural Killer Cell Therapies Catch Up to CAR T
Natural Killer Cell Therapies Catch Up to CAR T

There’s a new cell-based cancer immunotherapy on the block.

There’s a new cell-based cancer immunotherapy on the block.

immunotherapy
Flu Shot Ignites Immune Attack Against Cancer in Mice
Flu Shot Ignites Immune Attack Against Cancer in Mice
Ashley Yeager | Apr 1, 2020
Injecting the seasonal flu vaccine directly into clumps of malignant cells recruits immune cells to confront the cancer.
CAR T Cell Adds Scorpion Venom to Tackle Tumor Heterogeneity
CAR T Cell Adds Scorpion Venom to Tackle Tumor Heterogeneity
Amy Schleunes | Mar 24, 2020
A newly engineered CAR T cell that incorporates a peptide isolated from the venom of the deathstalker scorpion has broad brain tumor–binding capabilities that will be investigated in an upcoming clinical trial.
Novel DNA-Sensing Pathway Found in Human Cells, Absent in Mice
Novel DNA-Sensing Pathway Found in Human Cells, Absent in Mice
Catherine Offord | Jan 24, 2020
This previously unknown mechanism for spotting foreign genetic material in the cytoplasm launches antiviral defenses even when the well-known immune mediator STING is absent.
Side Effect of CAR T Therapy Caused by Pyroptosis: Mouse Study
Side Effect of CAR T Therapy Caused by Pyroptosis: Mouse Study
Kerry Grens | Jan 20, 2020
The immunotherapy induces a form of cell death in leukemia cells in mice that triggers cytokine release syndrome, a dangerous inflammatory reaction that occurs in some patients.
Immunology Leader Vincenzo Cerundolo Dies
Immunology Leader Vincenzo Cerundolo Dies
Ashley Yeager | Jan 16, 2020
The Oxford researcher’s work on lipid and peptide antigens revealed key mechanisms in inflammation, immunotherapy, and vaccination, which are being pursued in clinical trial treatments.
CAR T Immunotherapy May Find New Use in Treating Cardiac Fibrosis
CAR T Immunotherapy May Find New Use in Treating Cardiac Fibrosis
Emma Yasinski | Sep 11, 2019
Scientists show the approach can kill cells that cause hardening of heart tissue in mice.
Northwestern University Stem Cell Therapy Clinic Closes Abruptly
Northwestern University Stem Cell Therapy Clinic Closes Abruptly
Katarina Zimmer | Sep 6, 2019
A Chicago-based center that has long operated a clinical trial program for stem cell therapies, has stopped recruiting further patients as its chief, Richard Burt, leaves for a research sabbatical.
In Situ Vaccination: A Cancer Treatment a Century in the Making
In Situ Vaccination: A Cancer Treatment a Century in the Making
Emma Yasinski | Jul 25, 2019
Injecting immunostimulants directly into the tumor is not a new strategy to stimulate the immune system, but the approach has seen a surge of interest in recent years.
T Cell Proliferation Linked to CAR T Responses
T Cell Proliferation Linked to CAR T Responses
Ashley Yeager | Jul 15, 2019
Comparing the cells of cancer patients who did and did not respond to the immunotherapy could reveal biomarkers to predict who should receive it in the first place.