Opinion: Learning from Immunotherapy’s Recent Failures
Opinion: Learning from Immunotherapy’s Recent Failures
The promise of immunotherapy is real. We now need to figure out how to maximize the number of patients the approach benefits.
Opinion: Learning from Immunotherapy’s Recent Failures
Opinion: Learning from Immunotherapy’s Recent Failures

The promise of immunotherapy is real. We now need to figure out how to maximize the number of patients the approach benefits.

The promise of immunotherapy is real. We now need to figure out how to maximize the number of patients the approach benefits.

immunotherapy
Natural Killer Cells Prove Effective as a CAR Therapy in Mice
Natural Killer Cells Prove Effective as a CAR Therapy in Mice
Katarina Zimmer | Jul 6, 2018
Stem-cell–derived natural killer cells engineered in a similar way to CAR-T cells may pave the way to “off the shelf” cancer therapies that aren’t patient-specific.
“Public” T-Cell Receptors From Resistant People Fend Off HIV
“Public” T-Cell Receptors From Resistant People Fend Off HIV
Shawna Williams | Jun 8, 2018
The receptors, found in so-called elite controllers who don’t need medications to keep the virus in check, suggest a new path toward immunotherapy.
New Insights to Improve CAR T Cells’ Safety
New Insights to Improve CAR T Cells’ Safety
Vicki Brower | Jun 5, 2018
Drugs approved to treat rheumatoid arthritis block cytokines, the molecules responsible for severe side effects from the immunotherapy, and reduce symptoms in mice.
A T-Cell Tweak Combats Advanced Breast Cancer
A T-Cell Tweak Combats Advanced Breast Cancer
Ashley Yeager | Jun 5, 2018
The immunotherapy eliminated a woman’s metastatic lesions and kept her disease-free for two years.
Immunotherapy Drug Shows Promise for Melanoma, Lung Cancer
Immunotherapy Drug Shows Promise for Melanoma, Lung Cancer
Sukanya Charuchandra | Jun 4, 2018
Merck’s Keytruda extended the lives of lung cancer patients by several months and appeared to stop the progression of advanced melanoma.  
Immunotherapy More Effective in Men: Study
Immunotherapy More Effective in Men: Study
Kerry Grens | May 18, 2018
Women with metastatic cancer who were treated with a checkpoint inhibitor had a smaller benefit than did men.
Immune Therapy Improves Lung Cancer Patients’ Survival
Immune Therapy Improves Lung Cancer Patients’ Survival
Jim Daley | Apr 17, 2018
Pembrolizumab combined with chemotherapy nearly doubles survival rates and shrinks tumors in some individuals.
Antibody Combo Expands Response to Checkpoint Inhibitor in Mice
Antibody Combo Expands Response to Checkpoint Inhibitor in Mice
Kerry Grens | Apr 16, 2018
Genetic analyses uncover cellular hallmarks of bladder cancer tumors that don’t respond, but interfering with one of those characteristics in a mouse model causes tumors to shrink.  
New Ovarian Cancer Vaccine Shows Promise
New Ovarian Cancer Vaccine Shows Promise
Catherine Offord | Apr 12, 2018
A preliminary clinical trial finds that the personalized therapy improves survival rates and has no severe side-effects.