Final Straw for STAP?

Independent analysis uncovers suspected mouse cell mix-up, while stimulus-triggered acquisition of pluripotency lead author Haruko Obokata agrees to retract the work in full.

Written byTracy Vence
| 1 min read

Register for free to listen to this article
Listen with Speechify
0:00
1:00
Share

HARUKO OBOKATAStimulus-triggered acquisition of pluripotency (STAP) cells “are likely to have been obtained by combining two kinds of different cells,” The Japan Times reported today (June 4), neither of which were those lead author Haruko Obokata and her colleagues claimed to have used in two January Nature papers, according to RIKEN’s Takaho Endo. Performing an independent analysis of the STAP studies, Endo found evidence to suggest that the cells Obokata’s team created were not from an F1 mouse, but perhaps instead were from B6 and CD1 mice. He even suggested that the mix-up was intentional. “It is quite unlikely that this happens as a result of an accident or mistake,” Endo told reporters.

Meanwhile, Obakata—who was previously found by her institution to be guilty of research misconduct and last month (May 28) green-lighted the retraction of one of the two STAP papers—has agreed to retract the second publication, according to the Japan Daily Press. “She has agreed to retract both articles,” a RIKEN spokesperson told reporters.

Citing unnamed sources, The Asahi Shimbun reported that coauthor Charles Vacanti from Harvard Medical School and Brigham & Women’s Hospital “has also contacted the co-authors and expressed his intention to withdraw the article.”

For its part, Nature has said that it typically tries to get all authors to agree on a retraction before issuing one.

Update (June 4): A spokesperson for Nature said that “the authors are now in discussion with Nature ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies