Final Straw for STAP?

Independent analysis uncovers suspected mouse cell mix-up, while stimulus-triggered acquisition of pluripotency lead author Haruko Obokata agrees to retract the work in full.

| 1 min read

Register for free to listen to this article
Listen with Speechify
0:00
1:00
Share

HARUKO OBOKATAStimulus-triggered acquisition of pluripotency (STAP) cells “are likely to have been obtained by combining two kinds of different cells,” The Japan Times reported today (June 4), neither of which were those lead author Haruko Obokata and her colleagues claimed to have used in two January Nature papers, according to RIKEN’s Takaho Endo. Performing an independent analysis of the STAP studies, Endo found evidence to suggest that the cells Obokata’s team created were not from an F1 mouse, but perhaps instead were from B6 and CD1 mice. He even suggested that the mix-up was intentional. “It is quite unlikely that this happens as a result of an accident or mistake,” Endo told reporters.

Meanwhile, Obakata—who was previously found by her institution to be guilty of research misconduct and last month (May 28) green-lighted the retraction of one of the two STAP papers—has agreed to retract the second publication, according to the Japan Daily Press. “She has agreed to retract both articles,” a RIKEN spokesperson told reporters.

Citing unnamed sources, The Asahi Shimbun reported that coauthor Charles Vacanti from Harvard Medical School and Brigham & Women’s Hospital “has also contacted the co-authors and expressed his intention to withdraw the article.”

For its part, Nature has said that it typically tries to get all authors to agree on a retraction before issuing one.

Update (June 4): A spokesperson for Nature said that “the authors are now in discussion with Nature ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Keywords

Meet the Author

  • Tracy Vence

    This person does not yet have a bio.
Share
Image of a woman in a microbiology lab whose hair is caught on fire from a Bunsen burner.
April 1, 2025, Issue 1

Bunsen Burners and Bad Hair Days

Lab safety rules dictate that one must tie back long hair. Rosemarie Hansen learned the hard way when an open flame turned her locks into a lesson.

View this Issue
Conceptual image of biochemical laboratory sample preparation showing glassware and chemical formulas in the foreground and a scientist holding a pipette in the background.

Taking the Guesswork Out of Quality Control Standards

sartorius logo
An illustration of PFAS bubbles in front of a blue sky with clouds.

PFAS: The Forever Chemicals

sartorius logo
Unlocking the Unattainable in Gene Construction

Unlocking the Unattainable in Gene Construction

dna-script-primarylogo-digital
Concept illustration of acoustic waves and ripples.

Comparing Analytical Solutions for High-Throughput Drug Discovery

sciex

Products

Green Cooling

Thermo Scientific™ Centrifuges with GreenCool Technology

Thermo Fisher Logo
Singleron Avatar

Singleron Biotechnologies and Hamilton Bonaduz AG Announce the Launch of Tensor to Advance Single Cell Sequencing Automation

Zymo Research Logo

Zymo Research Launches Research Grant to Empower Mapping the RNome

Magid Haddouchi, PhD, CCO

Cytosurge Appoints Magid Haddouchi as Chief Commercial Officer