Studies of the response to microbial infection in Drosophila have taught us much about the conserved features of the innate immune response. In the October 23 Proceedings of the National Academy of Sciences, Ennio De Gregorio and colleagues at the CNRS Centre de Genetique Moleculaire, Gif-sur-Yvette, France, describe a genome-wide analysis of the Drosophila immune response (Proc Natl Acad Sci USA 2001, 98:12590-12595).They used high-density oligonucleotide microarrays to probe over 13,000 genes
Studies of the response to microbial infection in
They used high-density oligonucleotide microarrays to probe over 13,000 genes following septic injury or natural bacterial infection. They identified about 400 DIRGs,
Study of the large number of DIRGs representing unknown genes will provide new insights into innate immunity in flies and man.
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A new system that enables researchers to uniquely tag monoclonal antibodies for use in microscopy could help simplify complex imaging studies.
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Discover how single-molecule Fiber-seq is revealing unexpected mechanisms of transcription factor regulation, chromatin accessibility, and essential gene activation at CpG-island promoters.
Explore how emerging biomarker research and ultrasensitive multiplex proteomics are revealing molecular signatures associated with neurodegeneration, inflammation, and disease progression in amyotrophic lateral sclerosis (ALS).
Explore how in vivo CAR-neutrophil engineering and advanced light-sheet imaging are opening new avenues for studying and targeting glioblastoma and other solid tumors.
Explore practical strategies for designing, optimizing, and validating qPCR assays to improve specificity, reproducibility, and confidence across routine and high-throughput gene expression studies.
Automation can help to increase efficiency and reproducibility, but often comes at a significant cost. The ASSIST PLUS pipetting robot streamlines workflows at an affordable price, offering accessible automation with minimal programming requirements.
Corning® Cell Strainers are sterile, easy-to-use devices for rapidly isolating primary cells to consistently obtain a uniform single-cell suspension from tissues. Applications include stem cells and primary cells.
Real time imaging shouldn't outlast your cell surface stain. CellBrite® Steady: cell surface staining kits with fluorescent membrane dye plus enhancer for imaging live cell surface for several hours to days.
Partnership brings Monod Bio’s LuxSit luciferase and NovoBodies to SignalChem Biotech’s custom assay services
