Gene Jumped to All Three Domains of Life

By horizontal gene transfer, an antibacterial gene family has dispersed to a plant, an insect, several fungi, and an archaeon.

kerry grens
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WIKIMIEDIA, NOAAHorizontal gene transfer—the passing of DNA from one organism to another—is a prevalent among bacteria, and has even occurred between distantly related organisms, such as animals and bacteria. In a study published in eLife last week (November 25), researchers demonstrated for the first time that an antibacterial gene family has made the rounds across the three domains of life, from bacteria to archaea and eukaryotes.

“It is the first discovery of a functional antibacterial gene in Archaea,” Vanderbilt University’s Seth Bordenstein, who directed the study, said in a press release.

The results open up a new avenue for searching for antibiotics—in archaea. The gene family Bordenstein’s team studied is an enzyme that can deconstruct the bacterial wall.

Study coauthor Anna-Louise Reysenbach, a Portland State University microbiologist, said in the release that she had often wondered how these archaea, which live near hydrothermal vents, compete for resources with neighboring bacteria. “Through this paper, we show that the smart archaeal ‘bugs’ do so by stealing genes from their bacterial ‘mates’ and competitors. This points to Archaea being good, as yet relatively untapped targets for exploring new antibacterial drugs.”

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  • kerry grens

    Kerry Grens

    Kerry served as The Scientist’s news director until 2021. Before joining The Scientist in 2013, she was a stringer for Reuters Health, the senior health and science reporter at WHYY in Philadelphia, and the health and science reporter at New Hampshire Public Radio. Kerry got her start in journalism as a AAAS Mass Media fellow at KUNC in Colorado. She has a master’s in biological sciences from Stanford University and a biology degree from Loyola University Chicago.

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