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Artist’s rendering of various orange and pink colored bacteria
Q&A: What if Immune Cells Don’t Actually Detect Viruses and Bacteria?
The Scientist spoke with Jonathan Kagan about his idea that immune cells respond to “errors” made by unsuccessful pathogens, not the pathogens themselves.
Q&A: What if Immune Cells Don’t Actually Detect Viruses and Bacteria?
Q&A: What if Immune Cells Don’t Actually Detect Viruses and Bacteria?

The Scientist spoke with Jonathan Kagan about his idea that immune cells respond to “errors” made by unsuccessful pathogens, not the pathogens themselves.

The Scientist spoke with Jonathan Kagan about his idea that immune cells respond to “errors” made by unsuccessful pathogens, not the pathogens themselves.

antibiotics
Pseudomonas aeruginosa biofilm
Double Agents: Engineered Bacteria Tackle Pathogenic Biofilms in Mice
Katherine Irving | Jan 26, 2023 | 3 min read
Mycoplasma pneumoniae with pathogenic genes replaced by biofilm-degrading ones enhance survival in a mouse model of ventilator-associated pneumonia.
Person taking antibiotic pill
What Happens to the Gut Microbiome After Taking Antibiotics?
Sophie Fessl, PhD | May 5, 2022 | 5 min read
Studies are finding that a single course of antibiotics alters the gut microbiomes of healthy volunteers—and that it can take months or even years to recover the original species composition.
Brush Up: Quorum Sensing in Bacteria and Beyond
Brush Up: Quorum Sensing in Bacteria and Beyond
Deanna MacNeil, PhD | 4 min read
Microbes communicate with quorum sensing to coordinate their behavior in response to how many neighbors they have.
Baby with spotted onsie about to get injection of vaccine
Antibiotics Tied to Lower Effectiveness of Childhood Vaccines
Natalia Mesa, PhD | Apr 28, 2022 | 2 min read
Use of the drugs in children under the age of two was associated with lower antibody levels after the jabs—perhaps, researchers suggest, due to microbiome alterations.
Translucent, red-orange organs are shown inside a person’s transparent, blue torso. One region zooms in on blue lung alveoli covered by bright orange microbes.
Bacteria in the Lungs Can Regulate Autoimmunity in Rat Brains
Dan Robitzski | Mar 17, 2022 | 4 min read
Making specific alterations to the bacterial population in a rat’s lungs either better protects the animals against multiple sclerosis–like symptoms or makes them more vulnerable, a study finds—the first demonstration of a lung-brain axis.
Salmonella living within macrophages can survive antibiotic treatment and potentially give rise to resistance by two different mechanisms that slow or arrest their growth.
Bacteria Go Dormant to Survive Antibiotics and Restart Infections
Niki Spahich, PhD | 3 min read
In Salmonella, two seemingly similar antibiotic survival strategies result from very different molecular mechanisms.
Photo of a tiger moth
Antibiotics Given to Moths Spur Upregulation of Growth Genes
Devin A. Reese, PhD | Mar 1, 2022 | 2 min read
A new study has identified a molecular tradeoff between growth and immunity in moths in response to the administration of subtherapeutic doses of antibiotics, a common practice in animal husbandry.
a man collects water using a fishing pole and can
World’s Rivers Rife with Drugs: Study
Christie Wilcox, PhD | Feb 15, 2022 | 2 min read
Levels of pharmaceuticals considered unsafe for aquatic organisms were found at more than one-quarter of sampling sites.
Antibiotics May Influence Brain Development
Antibiotics May Influence Brain Development
Roni Dengler, PhD | 3 min read
Low doses of continuous penicillin exposure altered mouse pups’ microbiomes and gene expression in brain areas associated with emotional and cognitive function.
elongated blue bacterial cells on a reddish-brown background
Gut Microbiome May Help or Hinder Defenses Against SARS-CoV-2
Bianca Nogrady | Aug 31, 2021 | 7 min read
The health of the microbial community is associated with COVID-19 severity, but it’s not yet clear if the relationship is causal.
Julius Schachter, Renowned Chlamydia Researcher, Dies at 84
Max Kozlov | Jan 12, 2021 | 2 min read
The UCSF microbiologist pioneered investigations into the deadly disease starting in the late 1960s that have led to the near eradication of trachoma, a chlamydia-related eye infection.
Discover new treatments for pandemic diseases
Treatments for Disease Pandemics
The Scientist’s Creative Services Team | 1 min read
Researchers develop new vaccines and therapeutics to combat the spread of infectious diseases.
Laser-Triggered Nanobubbles Blast a Path into Biofilms
Jonathan Wosen | Apr 1, 2020 | 4 min read
Researchers could one day use the method to deliver antibiotics to topical wounds infected by hard-to-treat masses of bacteria.
Artificial Intelligence Discovers Potent Antibiotic
Amy Schleunes | Feb 22, 2020 | 2 min read
Researchers used a machine-learning platform to test more than 100 million molecules for antibacterial activity.
38447-ts-antibiotic-resistance-webinar-banner-jp800x560
Understanding Our Enemies: Identifying Mechanisms of Antibiotic Resistance
The Scientist’s Creative Services Team | 1 min read
Researchers sample and sequence bacteria from biological and environmental sources to learn how to overcome selective pressure
antibiotics antibiotics resistance persister bacteria bacteriophage
Opinion: We Need More than New Antibiotics to Fight Resistance
Neil S. Greenspan and Arturo Casadevall | Nov 1, 2019 | 3 min read
Metabolic disrupters, phages, and other approaches are going to be needed to treat the broadest possible range of patients infected by bacterial pathogens resistant to multiple drugs.
Image of the Day: Mother Machine
Emily Makowski | Sep 20, 2019 | 1 min read
Bacteria grow and divide in microfluidic channels.
The Scientist Speaks Podcast – Episode 3
The Scientist’s Creative Services Team | 1 min read
Tackling Antibiotic Resistance: Viruses to the Rescue
researcher stuart levy scientist physician tufts antibiotic resistance
Stuart Levy, Antibiotic Resistance Researcher, Dies
Emily Makowski | Sep 11, 2019 | 2 min read
The Tufts University biologist and physician sounded the alarm on the effects of antibiotic use in animals.
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