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Conceptional image of two pills covered with a circuit-board pattern.
Harnessing the Power of AI to Design Novel Antibiotics
Generative artificial intelligence allowed researchers to design new, synthesizable antibiotics against a dangerous and often drug-resistant human pathogen.
Harnessing the Power of AI to Design Novel Antibiotics
Harnessing the Power of AI to Design Novel Antibiotics

Generative artificial intelligence allowed researchers to design new, synthesizable antibiotics against a dangerous and often drug-resistant human pathogen.

Generative artificial intelligence allowed researchers to design new, synthesizable antibiotics against a dangerous and often drug-resistant human pathogen.

antibiotics

Vet giving vaccines to pigs
Antimicrobial Resistance: The Silent Pandemic
Danielle Gerhard, PhD | Jun 30, 2023 | 9 min read
Scientists continue to ring alarm bells about the risks associated with the continued misuse of antimicrobials and advocate for innovative treatments, improved surveillance, and greater public health education.
bacteria inside a biofilm
How Bacterial Communities Divvy up Duties
Holly Barker, PhD | Jun 1, 2023 | 10+ min read
Biofilms are home to millions of microbes, but disrupting their interactions could produce more effective antibiotics.
Industrial bioreactor with scientist in personal protective equipment
Introduction to Bioprocessing
Amielle Moreno, PhD | 7 min read
Bioprocessing employs the transformative power of biochemistry to drive sustainable production and pharmaceutical development.
The Biofilm Life Cycle
Infographic: Stages of Biofilm Formation
Holly Barker, PhD | Jun 1, 2023 | 1 min read
Free-swimming bacteria settle on a surface to cooperate and form a protective biofilm.
A cluster of spiral-shaped Treponema pallidum bacteria, the causative agent of syphilis.
Science Falls Behind as Syphilis Stages Another Comeback
Bhargavi Duvvuri, Undark | Feb 21, 2023 | 6 min read
Syphilis is among the oldest known sexually-transmitted infections. Scientists still struggle to detect and treat it.
Brush Up: Quorum Sensing in Bacteria and Beyond
Brush Up: Quorum Sensing in Bacteria and Beyond
Deanna MacNeil, PhD | 4 min read
Microbes communicate with quorum sensing to coordinate their behavior in response to how many neighbors they have.
Artist’s rendering of various orange and pink colored bacteria
Q&A: What if Immune Cells Don’t Actually Detect Viruses and Bacteria?
Dan Robitzski | Feb 3, 2023 | 10+ min read
The Scientist spoke with Jonathan Kagan about his idea that immune cells respond to “errors” made by unsuccessful pathogens, not the pathogens themselves.
Pseudomonas aeruginosa biofilm
Double Agents: Engineered Bacteria Tackle Pathogenic Biofilms in Mice
Katherine Irving | Jan 26, 2023 | 3 min read
Mycoplasma pneumoniae with pathogenic genes replaced by biofilm-degrading ones enhance survival in a mouse model of ventilator-associated pneumonia.
Discover new treatments for pandemic diseases
Treatments for Disease Pandemics
The Scientist | 1 min read
Researchers develop new vaccines and therapeutics to combat the spread of infectious diseases.
Person taking antibiotic pill
What Happens to the Gut Microbiome After Taking Antibiotics?
Sophie Fessl, PhD | May 5, 2022 | 5 min read
Studies are finding that a single course of antibiotics alters the gut microbiomes of healthy volunteers—and that it can take months or even years to recover the original species composition.
Baby with spotted onsie about to get injection of vaccine
Antibiotics Tied to Lower Effectiveness of Childhood Vaccines
Natalia Mesa, PhD | Apr 28, 2022 | 2 min read
Use of the drugs in children under the age of two was associated with lower antibody levels after the jabs—perhaps, researchers suggest, due to microbiome alterations.
38447-ts-antibiotic-resistance-webinar-banner-jp800x560
Understanding Our Enemies: Identifying Mechanisms of Antibiotic Resistance
The Scientist | 1 min read
Researchers sample and sequence bacteria from biological and environmental sources to learn how to overcome selective pressure
Translucent, red-orange organs are shown inside a person’s transparent, blue torso. One region zooms in on blue lung alveoli covered by bright orange microbes.
Bacteria in the Lungs Can Regulate Autoimmunity in Rat Brains
Dan Robitzski | Mar 17, 2022 | 4 min read
Making specific alterations to the bacterial population in a rat’s lungs either better protects the animals against multiple sclerosis–like symptoms or makes them more vulnerable, a study finds—the first demonstration of a lung-brain axis.
Salmonella living within macrophages can survive antibiotic treatment and potentially give rise to resistance by two different mechanisms that slow or arrest their growth.
Bacteria Go Dormant to Survive Antibiotics and Restart Infections
Niki Spahich, PhD | Mar 7, 2022 | 3 min read
In Salmonella, two seemingly similar antibiotic survival strategies result from very different molecular mechanisms.
The Scientist Speaks Podcast – Episode 3
The Scientist | 1 min read
Tackling Antibiotic Resistance: Viruses to the Rescue
Photo of a tiger moth
Antibiotics Given to Moths Spur Upregulation of Growth Genes
Devin A. Reese, PhD | Mar 1, 2022 | 2 min read
A new study has identified a molecular tradeoff between growth and immunity in moths in response to the administration of subtherapeutic doses of antibiotics, a common practice in animal husbandry.
a man collects water using a fishing pole and can
World’s Rivers Rife with Drugs: Study
Christie Wilcox, PhD | Feb 15, 2022 | 2 min read
Levels of pharmaceuticals considered unsafe for aquatic organisms were found at more than one-quarter of sampling sites.
Antibiotics May Influence Brain Development
Antibiotics May Influence Brain Development
Roni Dengler, PhD | Jan 10, 2022 | 3 min read
Low doses of continuous penicillin exposure altered mouse pups’ microbiomes and gene expression in brain areas associated with emotional and cognitive function.
elongated blue bacterial cells on a reddish-brown background
Gut Microbiome May Help or Hinder Defenses Against SARS-CoV-2
Bianca Nogrady | Aug 31, 2021 | 7 min read
The health of the microbial community is associated with COVID-19 severity, but it’s not yet clear if the relationship is causal.
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