Genetic screens are powerful techniques to investigate gene function, dissect complex biological processes, and rapidly assess drug targets. Advances in CRISPR/Cas9 technology have led to remarkable progress in this relatively new field. The Scientist brings together a panel of experts to share their perspectives on genome-wide functional screening and applications in drug development. Attendees can interact with the panel during the live webinar by asking questions and sharing their experiences.
Topics to be covered:
- Application of genome-scale gain- and loss-of-function screening using the CRISPR system
- Identification of biomarkers associated with genetic vulnerabilities in genome-scale knockout screens
- Use of synthetic drug screens to evaluate drug efficacy in different tumor mutational backgrounds
Meet the Speakers:
Dr. Feng Zhang
Core Member
Broad Institute of MIT and Harvard
Keck Career Development Professor
Massachusetts Institute of Technology
Dr. Traver Hart
Assistant Professor
Department of Bioinformatics and Computational Biology
MD Anderson Cancer Center