Genetic Sequencing Uncovers New Options for Multiple Myeloma Patients

A small pilot study suggests the approach can identify effective treatments already approved for other cancers.

Written byShawna Williams
| 5 min read

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ABOVE: Mount Sinai Hospital researchers Samir Parekh and Deepak Perumal use DNA and RNA sequencing to help find new combinations of existing treatments for cancer patients.
MOUNT SINAI HEALTH SYSTEM

At first, Stuart Harshbarger thought he’d injured his back lifting furniture and boxes. When the pain started, in 2008, “we’d just moved from Detroit to New York,” he explains. But the pain was excruciating, so the then 45-year-old international management consultant saw a doctor, who tested him for multiple myeloma, a blood cancer that often causes back pain. He got the results by phone while on a business trip in Germany, and was “scared to death,” he remembers.

In the decade since, Harshbarger’s odyssey has been typical of that of many multiple myeloma patients—though he’s made it past the median survival time for the disease, six years. He’s been through a series of standard treatments, most of which worked for some ...

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Meet the Author

  • Shawna was an editor at The Scientist from 2017 through 2022. She holds a bachelor’s degree in biochemistry from Colorado College and a graduate certificate in science communication from the University of California, Santa Cruz. Previously, she worked as a freelance editor and writer, and in the communications offices of several academic research institutions. As news director, Shawna assigned and edited news, opinion, and in-depth feature articles for the website on all aspects of the life sciences. She is based in central Washington State, and is a member of the Northwest Science Writers Association and the National Association of Science Writers.

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