Genetic Sequencing Uncovers New Options for Multiple Myeloma Patients

A small pilot study suggests the approach can identify effective treatments already approved for other cancers.

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ABOVE: Mount Sinai Hospital researchers Samir Parekh and Deepak Perumal use DNA and RNA sequencing to help find new combinations of existing treatments for cancer patients.
MOUNT SINAI HEALTH SYSTEM

At first, Stuart Harshbarger thought he’d injured his back lifting furniture and boxes. When the pain started, in 2008, “we’d just moved from Detroit to New York,” he explains. But the pain was excruciating, so the then 45-year-old international management consultant saw a doctor, who tested him for multiple myeloma, a blood cancer that often causes back pain. He got the results by phone while on a business trip in Germany, and was “scared to death,” he remembers.

In the decade since, Harshbarger’s odyssey has been typical of that of many multiple myeloma patients—though he’s made it past the median survival time for the disease, six years. He’s been through a series of standard treatments, most of which worked for some ...

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Meet the Author

  • Shawna Williams

    Shawna was an editor at The Scientist from 2017 through 2022. She holds a bachelor's degree in biochemistry from Colorado College and a graduate certificate and science communication from the University of California, Santa Cruz.

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