mice on wheel and ground
Exercise-Associated Protein Boosts Brain Function in Mice
A study that transfused plasma from active to inactive mice suggests the protein clusterin enhances cognition.
ABOVE: © ISTOCK.COM, JAMESBREY
Exercise-Associated Protein Boosts Brain Function in Mice
Exercise-Associated Protein Boosts Brain Function in Mice

A study that transfused plasma from active to inactive mice suggests the protein clusterin enhances cognition.

A study that transfused plasma from active to inactive mice suggests the protein clusterin enhances cognition.

ABOVE: © ISTOCK.COM, JAMESBREY

RNA sequencing

Image of the microscopic view of an infectious virus cell, RNA.
Opinion: The Pandemic and the RNA Sequencing Gap
Robert Ross | Sep 1, 2021
RNA sequencing technology lags far behind researchers’ ability to decode and understand DNA. The COVID-19 pandemic has highlighted this dangerous shortcoming.
Photograph from 1918 influenza pandemic shows mask-wearing women holding stretchers at backs of ambulances in Saint Louis, Missouri.
100-Year-Old Lungs Yield Genetic Samples of 1918 Flu Viruses
Christie Wilcox | May 18, 2021
Influenza RNA sequences from three sets of lungs preserved in formalin since 1918 provide new insights into the deadly pandemic.
Visualize Transcript Location with Spatial Biology Techniques
Unraveling the Cellular and Subcellular Landscape Using Spatial Biology
The Scientist Creative Services Team, Resolve Biosciences | Apr 12, 2022
How to visualize gene expression patterns in situ
early-life stress, histone, chromatin, epigenetics, epigenetic modification, methylation, DNA, protein, stress, adversity, mice, genetics, genomics
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Asher Jones | Mar 18, 2021
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
Identified: Molecular Predictors of Rheumatoid Arthritis Relapse
Ruth Williams | Jul 15, 2020
The presence of a particular set of RNAs in the blood forewarns of an onset of severe symptoms and points to the cells involved.
Technique Talk: Single-Cell Sequencing Experimental Design
Technique Talk: Single-Cell Sequencing Experimental Design
The Scientist Creative Services Team | Dec 21, 2021
Learn how to balance sample limitations and experimental methods for optimal single-cell sequencing results.
Image of the Day: Beetle Evolution
Emily Makowski | Nov 19, 2019
Plants, fungi, and bacteria likely contributed to insect diversity.
Spaceflight Alters Genes of Human Stem Cell–Derived Heart Cells
Emily Makowski | Nov 7, 2019
Cardiomyocytes made from iPSCs aboard the International Space Station had upregulated mitochondrial functioning.
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LabTalk Podcast - Hijacking Genes: Uncovering the Cause of Lineage Ambiguous Leukemia
The Scientist Creative Services Team | Oct 28, 2021
Chromosomal rearrangements reposition influential and often overlooked non-coding elements in the genome to hijack genes and cause cancer.
Increased Neuronal Activity Shortens Lifespan in Animals
Ruth Williams | Oct 16, 2019
Suppressing the natural age-related increase in neuronal excitation lengthens the lives of worms, and there are indications that the same may be true for mice and humans.
New Tools in the Works to Probe Adult Human Neurogenesis
Ashley Yeager | Oct 7, 2019
Conflicting results on the existence of new neurons in adults have researchers designing new ways to identify and count neuronal progenitors—and finally get to the bottom of neurogenesis.
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Technique Talk: Designing and Optimizing RNA-seq Experiments
The Scientist Creative Services Team | Aug 31, 2021
Learn how to select and perfect RNA-seq technologies to answer specific research questions.  
RNAs
Drug Discovery Techniques Open the Door to RNA-targeted Drugs
Amber Dance | Jun 1, 2019
New ways to search for druggable RNAs and matching small molecules
Neural Cell Types Tied to Autism Identified in Single-Cell Study
Ruth Williams | May 16, 2019
An RNA analysis of human brain cells reveals gene expression changes in cortical neurons and microglia linked to autism spectrum disorder (ASD).
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Studying Cellular Heterogeneity in the Lower Urinary Tract with Spatial Transcriptomics
The Scientist Creative Services Team in collaboration with Advanced Cell Diagnostics | Aug 24, 2021
Anushka Dikshit, Kit Fuhrman, and Diya Joseph present how to leverage in situ hybridization and spatial genomic profiling for prostate cancer research.
Analysis of 2,000 Brains Provides Clues to Schizophrenia, Autism
Catherine Offord | Dec 14, 2018
The PsychENCODE project delves into the DNA, RNA, and protein changes related to brain development and neuropsychiatric disorders, but researchers caution it’s just a first step toward treatment.
Genetic Sequencing Uncovers New Options for Multiple Myeloma Patients
Shawna Williams | Nov 1, 2018
A small pilot study suggests the approach can identify effective treatments already approved for other cancers.
Discovering the Secrets of Motor Neurons with Single Cell Sequencing
LabTalk Podcast - Discovering the Secrets of Motor Neurons with Single Cell Sequencing
The Scientist Creative Services Team, 10x Genomics | May 5, 2021
Researchers identify new motor neuron subgroups and gain insights into amyotrophic lateral sclerosis (ALS).
Genome, Exome, RNA Sequencing Applied to Pediatric Cancer Cases
Ashley Yeager | Oct 18, 2018
Combining data from the genetic testing techniques can guide patient care, scientists say.