Photo of Ankara Jain in his lab
Ankur Jain Explores RNA Aggregations in Neurodegenerative Disease
The MIT biologist studies how RNA molecules self-assemble and the role these accumulations may play in diseases such as ALS and Huntington’s.
Ankur Jain Explores RNA Aggregations in Neurodegenerative Disease
Ankur Jain Explores RNA Aggregations in Neurodegenerative Disease

The MIT biologist studies how RNA molecules self-assemble and the role these accumulations may play in diseases such as ALS and Huntington’s.

The MIT biologist studies how RNA molecules self-assemble and the role these accumulations may play in diseases such as ALS and Huntington’s.

RNA sequencing
3D rendering of a scanning electron micrograph of pink malignant cancer cells against a black background
Cancers Ramp Up Overall mRNA Expression as They Progress
Dan Robitzski | Jun 14, 2022
A technique for quantifying tumor mRNA production from messy tissue sample data uncovers an unexpected correlation between it and disease stage in 15 cancer types.
Ribonucleic acid strands consisting of nucleotides important for protein bio-synthesis
Katharina Höfer Probes the Machinery of Bacterial Gene Expression
Hannah Thomasy | Jun 13, 2022
The molecular biologist studies how chemical modifications to RNA building blocks change the way RNA regulates complex cellular processes.
Visualize Transcript Location with Spatial Biology Techniques
Unraveling the Cellular and Subcellular Landscape Using Spatial Biology
The Scientist Creative Services Team and Resolve Biosciences
How to visualize gene expression patterns in situ
mice on wheel and ground
Exercise-Associated Protein Boosts Brain Function in Mice
Chloe Tenn | Dec 9, 2021
A study that transfused plasma from active to inactive mice suggests the protein clusterin enhances cognition.
Image of the microscopic view of an infectious virus cell, RNA.
Opinion: The Pandemic and the RNA Sequencing Gap
Robert Ross | Sep 1, 2021
RNA sequencing technology lags far behind researchers’ ability to decode and understand DNA. The COVID-19 pandemic has highlighted this dangerous shortcoming.
Technique Talk: Single-Cell Sequencing Experimental Design
Technique Talk: Single-Cell Sequencing Experimental Design
The Scientist Creative Services Team
Learn how to balance sample limitations and experimental methods for optimal single-cell sequencing results.
Photograph from 1918 influenza pandemic shows mask-wearing women holding stretchers at backs of ambulances in Saint Louis, Missouri.
100-Year-Old Lungs Yield Genetic Samples of 1918 Flu Viruses
Christie Wilcox | May 18, 2021
Influenza RNA sequences from three sets of lungs preserved in formalin since 1918 provide new insights into the deadly pandemic.
early-life stress, histone, chromatin, epigenetics, epigenetic modification, methylation, DNA, protein, stress, adversity, mice, genetics, genomics
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Asher Jones | Mar 18, 2021
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
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LabTalk Podcast - Hijacking Genes: Uncovering the Cause of Lineage Ambiguous Leukemia
The Scientist Creative Services Team
Chromosomal rearrangements reposition influential and often overlooked non-coding elements in the genome to hijack genes and cause cancer.
Identified: Molecular Predictors of Rheumatoid Arthritis Relapse
Ruth Williams | Jul 15, 2020
The presence of a particular set of RNAs in the blood forewarns of an onset of severe symptoms and points to the cells involved.
Image of the Day: Beetle Evolution
Emily Makowski | Nov 19, 2019
Plants, fungi, and bacteria likely contributed to insect diversity.
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Technique Talk: Designing and Optimizing RNA-seq Experiments
The Scientist Creative Services Team
Learn how to select and perfect RNA-seq technologies to answer specific research questions.  
Spaceflight Alters Genes of Human Stem Cell–Derived Heart Cells
Emily Makowski | Nov 7, 2019
Cardiomyocytes made from iPSCs aboard the International Space Station had upregulated mitochondrial functioning.
Increased Neuronal Activity Shortens Lifespan in Animals
Ruth Williams | Oct 16, 2019
Suppressing the natural age-related increase in neuronal excitation lengthens the lives of worms, and there are indications that the same may be true for mice and humans.
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Studying Cellular Heterogeneity in the Lower Urinary Tract with Spatial Transcriptomics
The Scientist Creative Services Team in collaboration with Advanced Cell Diagnostics
Anushka Dikshit, Kit Fuhrman, and Diya Joseph present how to leverage in situ hybridization and spatial genomic profiling for prostate cancer research.
New Tools in the Works to Probe Adult Human Neurogenesis
Ashley Yeager | Oct 7, 2019
Conflicting results on the existence of new neurons in adults have researchers designing new ways to identify and count neuronal progenitors—and finally get to the bottom of neurogenesis.
RNAs
Drug Discovery Techniques Open the Door to RNA-targeted Drugs
Amber Dance | Jun 1, 2019
New ways to search for druggable RNAs and matching small molecules
Discovering the Secrets of Motor Neurons with Single Cell Sequencing
LabTalk Podcast - Discovering the Secrets of Motor Neurons with Single Cell Sequencing
The Scientist Creative Services Team and 10x Genomics
Researchers identify new motor neuron subgroups and gain insights into amyotrophic lateral sclerosis (ALS).
Neural Cell Types Tied to Autism Identified in Single-Cell Study
Ruth Williams | May 16, 2019
An RNA analysis of human brain cells reveals gene expression changes in cortical neurons and microglia linked to autism spectrum disorder (ASD).