ADVERTISEMENT
Illustraton of DNA double helix on purple background
Unbalanced Allele Expression Associated with Mutation, Disease
A study identifies nearly 3,000 genes where one allele tends to be expressed more than the other, but the findings ignited controversy in the field. 
Unbalanced Allele Expression Associated with Mutation, Disease
Unbalanced Allele Expression Associated with Mutation, Disease

A study identifies nearly 3,000 genes where one allele tends to be expressed more than the other, but the findings ignited controversy in the field. 

A study identifies nearly 3,000 genes where one allele tends to be expressed more than the other, but the findings ignited controversy in the field. 

RNA sequencing
Microscopy view of cancerous human cervix cells stained violet.
Why Some HPV Infections Carry More Cervical Cancer Risk
Dan Robitzski | Feb 2, 2023 | 5 min read
Where and how human papillomavirus integrates itself into the human genome steers the infection’s clinical outcomes, finds a large, multifaceted study.
Photo of Ankara Jain in his lab
Ankur Jain Explores RNA Aggregations in Neurodegenerative Disease
Hannah Thomasy | Oct 3, 2022 | 3 min read
The MIT biologist studies how RNA molecules self-assemble and the role these accumulations may play in diseases such as ALS and Huntington’s.
Visualize Transcript Location with Spatial Biology Techniques
Unraveling the Cellular and Subcellular Landscape Using Spatial Biology
The Scientist’s Creative Services Team and Resolve Biosciences | 1 min read
How to visualize gene expression patterns in situ
3D rendering of a scanning electron micrograph of pink malignant cancer cells against a black background
Cancers Ramp Up Overall mRNA Expression as They Progress
Dan Robitzski | Jun 14, 2022 | 4 min read
A technique for quantifying tumor mRNA production from messy tissue sample data uncovers an unexpected correlation between it and disease stage in 15 cancer types.
Ribonucleic acid strands consisting of nucleotides important for protein bio-synthesis
Katharina Höfer Probes the Machinery of Bacterial Gene Expression
Hannah Thomasy | Jun 13, 2022 | 3 min read
The molecular biologist studies how chemical modifications to RNA building blocks change the way RNA regulates complex cellular processes.
Technique Talk: Single-Cell Sequencing Experimental Design
Technique Talk: Single-Cell Sequencing Experimental Design
The Scientist’s Creative Services Team | 1 min read
Learn how to balance sample limitations and experimental methods for optimal single-cell sequencing results.
mice on wheel and ground
Exercise-Associated Protein Boosts Brain Function in Mice
Chloe Tenn | Dec 9, 2021 | 5 min read
A study that transfused plasma from active to inactive mice suggests the protein clusterin enhances cognition.
Image of the microscopic view of an infectious virus cell, RNA.
Opinion: The Pandemic and the RNA Sequencing Gap
Robert Ross | Sep 1, 2021 | 3 min read
RNA sequencing technology lags far behind researchers’ ability to decode and understand DNA. The COVID-19 pandemic has highlighted this dangerous shortcoming.
800x560-istock-1080830474
LabTalk Podcast - Hijacking Genes: Uncovering the Cause of Lineage Ambiguous Leukemia
The Scientist’s Creative Services Team | 1 min read
Chromosomal rearrangements reposition influential and often overlooked non-coding elements in the genome to hijack genes and cause cancer.
Photograph from 1918 influenza pandemic shows mask-wearing women holding stretchers at backs of ambulances in Saint Louis, Missouri.
100-Year-Old Lungs Yield Genetic Samples of 1918 Flu Viruses
Christie Wilcox, PhD | May 18, 2021 | 2 min read
Influenza RNA sequences from three sets of lungs preserved in formalin since 1918 provide new insights into the deadly pandemic.
early-life stress, histone, chromatin, epigenetics, epigenetic modification, methylation, DNA, protein, stress, adversity, mice, genetics, genomics
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Asher Jones | Mar 18, 2021 | 5 min read
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
800x560-thumbnail-sept-27
Technique Talk: Designing and Optimizing RNA-seq Experiments
The Scientist’s Creative Services Team | 1 min read
Learn how to select and perfect RNA-seq technologies to answer specific research questions.  
Identified: Molecular Predictors of Rheumatoid Arthritis Relapse
Ruth Williams | Jul 15, 2020 | 4 min read
The presence of a particular set of RNAs in the blood forewarns of an onset of severe symptoms and points to the cells involved.
Image of the Day: Beetle Evolution
Emily Makowski | Nov 19, 2019 | 1 min read
Plants, fungi, and bacteria likely contributed to insect diversity.
800x560-sept-21-2021
Studying Cellular Heterogeneity in the Lower Urinary Tract with Spatial Transcriptomics
The Scientist Creative Services Team in collaboration with Advanced Cell Diagnostics | 2 min read
Anushka Dikshit, Kit Fuhrman, and Diya Joseph present how to leverage in situ hybridization and spatial genomic profiling for prostate cancer research.
Spaceflight Alters Genes of Human Stem Cell–Derived Heart Cells
Emily Makowski | Nov 7, 2019 | 3 min read
Cardiomyocytes made from iPSCs aboard the International Space Station had upregulated mitochondrial functioning.
Increased Neuronal Activity Shortens Lifespan in Animals
Ruth Williams | Oct 16, 2019 | 3 min read
Suppressing the natural age-related increase in neuronal excitation lengthens the lives of worms, and there are indications that the same may be true for mice and humans.
Discovering the Secrets of Motor Neurons with Single Cell Sequencing
LabTalk Podcast - Discovering the Secrets of Motor Neurons with Single Cell Sequencing
The Scientist’s Creative Services Team and 10x Genomics | 1 min read
Researchers identify new motor neuron subgroups and gain insights into amyotrophic lateral sclerosis (ALS).
New Tools in the Works to Probe Adult Human Neurogenesis
Ashley Yeager | Oct 7, 2019 | 6 min read
Conflicting results on the existence of new neurons in adults have researchers designing new ways to identify and count neuronal progenitors—and finally get to the bottom of neurogenesis.
ADVERTISEMENT