Genome Digest

What researchers are learning as they sequence, map, and decode species’ genomes

Written byKate Yandell
| 5 min read

Register for free to listen to this article
Listen with Speechify
0:00
5:00
Share

HeLa cellsFLICKR, GE HEALTHCARE

Cell type: HeLa cells, the cervical tumor cells of Henrietta Lacks
Genome size: ~3.2 billion base pairs

HeLa cells, the first cells ever to be grown immortally in culture, have supported some of the greatest scientific achievements, including the development of the polio vaccine and the discovery that the human papilloma virus can cause cervical cancer. They were sampled in 1951 from the cervical tumor of a woman named Henrietta Lacks who died at Johns Hopkins Hospital in Baltimore of cervical cancer, and in the years since they have contributed to more than 60,000 publications.

Now, for the first time, HeLa cells have been sequenced, and the results show that they are vastly different from ordinary human cells. Previous work had shown that they have ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

Share
July Digest 2025
July 2025, Issue 1

What Causes an Earworm?

Memory-enhancing neural networks may also drive involuntary musical loops in the brain.

View this Issue
Screening 3D Brain Cell Cultures for Drug Discovery

Screening 3D Brain Cell Cultures for Drug Discovery

Explore synthetic DNA’s many applications in cancer research

Weaving the Fabric of Cancer Research with Synthetic DNA

Twist Bio 
Illustrated plasmids in bright fluorescent colors

Enhancing Elution of Plasmid DNA

cytiva logo
An illustration of green lentiviral particles.

Maximizing Lentivirus Recovery

cytiva logo

Products

The Scientist Placeholder Image

Sino Biological Sets New Industry Standard with ProPure Endotoxin-Free Proteins made in the USA

sartorius-logo

Introducing the iQue 5 HTS Platform: Empowering Scientists  with Unbeatable Speed and Flexibility for High Throughput Screening by Cytometry

parse_logo

Vanderbilt Selects Parse Biosciences GigaLab to Generate Atlas of Early Neutralizing Antibodies to Measles, Mumps, and Rubella

shiftbioscience

Shift Bioscience proposes improved ranking system for virtual cell models to accelerate gene target discovery