In the December 18 Proceedings of the National Academy of Sciences, Xavier Morin and colleagues describe a gene-trap strategy that generates green fluorescent protein (GFP) fusions and allows the study of protein distribution and subcellular localization in living flies (Proc Natl Acad Sci USA 2001, 98:15050-15055).They created a protein-trap transposon (PTT), a P element containing an artificial exon encoding GFP and flanked by splice acceptor and donor sequences. They derived over 600 fluoresc
In the December 18
They created a protein-trap transposon (PTT), a P element containing an artificial exon encoding GFP and flanked by splice acceptor and donor sequences. They derived over 600 fluorescent
Characterization of several of these revealed that in most cases splicing occurred correctly and fusions recapitulated endogenous expression of the trapped gene. Over 40% of characterized lines correspond to genes that were not predicted by the
These fluttering sensations are the brain’s reaction to certain emotions, which can be amplified or soothed by the gut’s own “bugs".
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Olga Anczukow and Ryan Englander discuss how transcriptome splicing affects immune system function in lung cancer.
In our next roundtable webinar, learn how scientists leverage spatial biology to map tissues, uncover cellular interactions, and advance disease research.
Discover how scientists use the latest gene editing tools to advance health research.
Fujirebio's Lumipulse® G pTau217/β-Amyloid 1-42 Plasma Ratio test has the potential to shorten the Alzheimer's disease diagnostic journey and enable earlier intervention through its accessibility and high diagnostic performance.
Ten-year Agreement to Provide a Secure, AI-enabled Forensic Laboratory Information Management System Supporting DHS Forensic, Scientific, and Testing Services
deliver robust, reproducible solutions for sample preparation enabling a new era of end-to-end standardization in proteomics
Enables higher-throughput, cost effective single-cell sequencing
Enables ultra-low variant detection across a range of key MRD targets in AML, including very large FLT3-ITDs
