Progressive heart failure and death can occur following myocardial infarction due to ventricular remodelling and fibrosis. Neoangiogenesis occurs normally within the infarcted tissue, but the new capillary network is unable to support the greater demands of the hypertrophied myocardium and remaining myocytes are unable to reconstitute the necrotic tissue.
In the April
They used selected bone marrow cells from human donors and athymic rat recipients with ligation-induced coronary thrombosis as an experimental model of infarction. Kocher