Following the recent linkurl:failure; of a linkurl:Merck HIV vaccine,; the NIH has still not decided whether to continue with planned clinical trials of a similar HIV vaccine. Yesterday (December 12), the AIDS Vaccine Research Committee of the National Institute of Allergy and Infectious Diseases met to discuss the PAVE100 study, which was suspended after linkurl:data from the Merck trials; came back. Both vaccines use an linkurl:adenovirus vector; to deliver HIV genes and replicate their proteins. The data from the Merck trials suggested that the vaccine might have actually made people with pre-existing immunity to adenovirus more susceptible to HIV infection, leading to the halting of the PAVE100 trials. The sentiment at yesterday's meeting seemed to be that the vaccines are different enough to warrant going ahead with the PAVE100 study, linkurl:Anthony Fauci,; the director of the National Institute of Allergy and Infectious Diseases told __The Scientist.__ The PAVE100 vaccine also...

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