Prions that cause scrapie, bovine spongiform encephalopathy (BSE) and Creutzfeldt-Jakob disease do not initiate an immune response, probably because they do not contain nucleic acids. So immune prophylaxis to these diseases is difficult to achieve. But in 20 July
Sethi
"The most likely explanation is the stimulation of TLR9-expressing cells of the innate immune system such as macrophages, monocytes and dendritic cells. CpG oligodeoxynucleotides have not been shown to have adverse...