Researchers watch the protein condensin in action.
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© IKUMI KAYAMA/STUDIO KAYAMA
Researchers anchored a DNA strand to a quartz surface using streptavidin and watched as the protein complex condensin latched to the nucleic acid and formed loops. Contrary to previously established computational models of loop extrusion, which predicted that the two sides of the DNA strand would be reeled in simultaneously, findings from this study suggest that condensin anchors itself to a piece of DNA and reels in the other side.
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A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.
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