In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.

The University of Oregon scientist studied the structure and function of chromatin, with the intent of designing new therapeutic tools.

In this webinar brought to you by 10x Genomics, experts will discuss how to successfully prepare nuclei suspensions for Single Cell Multiome ATAC + Gene Expression experiments.

In this webinar brought to you by 10x Genomics, experts will discuss tips for running Chromium Single Cell Multiome ATAC + Gene Expression experiments in your lab.

PCR moves into the laundry room, while insect colonies take up residence in the shower.

The DNA-protein complex has branches that fold back on themselves.

The Dana-Farber Cancer Institute researcher is developing cancer therapeutics based on how the physical structure of DNA contributes to the disease.

Telomeres in cancer cells exposed to oxidative stress got shorter and stickier.

Researchers describe their tools for probing how the physical shape of the genome affects genes’ function.

Researchers watch the protein condensin in action.

Researchers map learning-induced chromatin alterations in mouse brain cells, and find that many affect autism-associated genes.

New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.

The switch from maternal factors involves dynamic reprogramming of the zygotic genome.

New microscopy techniques reveal that heterochromatin—the condensed, seemingly dormant portions of DNA—is not as dense as scientists once thought.

A test tube-based genome-labeling technique has been brought under the microscope.

See how researchers visualize regions of active genes.

A study on human cells reveals how cellular aging affects the 3-D architecture of chromosomes.

A growing toolbox for surveying the activity of entire genomes

By manipulating DNA sequences that guide genome-folding, researchers confirm an existing model of chromatin structure inside the nucleus.