Signaling Dynamics Fine-Tune Gene Expression
Signaling Dynamics Fine-Tune Gene Expression
The dynamic behavior of a transcriptional activator can be used to specify the activity level of its target gene, a study suggests.
Signaling Dynamics Fine-Tune Gene Expression
Signaling Dynamics Fine-Tune Gene Expression

The dynamic behavior of a transcriptional activator can be used to specify the activity level of its target gene, a study suggests.

The dynamic behavior of a transcriptional activator can be used to specify the activity level of its target gene, a study suggests.

chromatin
Dinoflagellate Genome Structure Unlike Any Other Known
Dinoflagellate Genome Structure Unlike Any Other Known
Amanda Heidt | May 10, 2021
The transcription of DNA drives the remarkably tidy organization of chromosomes in the dinoflagellate Symbiodinium microadriaticum.
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Asher Jones | Mar 18, 2021
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
Molecular Biologist Jeff McKnight Dies at 36
Molecular Biologist Jeff McKnight Dies at 36
Amanda Heidt | Oct 8, 2020
The University of Oregon scientist studied the structure and function of chromatin, with the intent of designing new therapeutic tools.
Amid the COVID-19 Pandemic, Some Scientists Bring the Bench Home
Amid the COVID-19 Pandemic, Some Scientists Bring the Bench Home
Emma Yasinski | May 13, 2020
PCR moves into the laundry room, while insect colonies take up residence in the shower.
Image of the Day: Chromatin Forest
Image of the Day: Chromatin Forest
Emily Makowski | Jan 14, 2020
The DNA-protein complex has branches that fold back on themselves.
Cigall Kadoch Unravels Chromatin’s Role in Cancer
Cigall Kadoch Unravels Chromatin’s Role in Cancer
Chia-Yi Hou | Sep 1, 2019
The Dana-Farber Cancer Institute researcher is developing cancer therapeutics based on how the physical structure of DNA contributes to the disease.
Image of the Day: Sticky Telomeres
Image of the Day: Sticky Telomeres
Chia-Yi Hou | May 16, 2019
Telomeres in cancer cells exposed to oxidative stress got shorter and stickier.
Imaging Chromatin to Deduce Function from Form
Imaging Chromatin to Deduce Function from Form
Marissa Fessenden | Dec 1, 2018
Researchers describe their tools for probing how the physical shape of the genome affects genes’ function.
Infographic: Packing DNA
Infographic: Packing DNA
Diana Kwon | May 31, 2018
Researchers watch the protein condensin in action.
Learning Opens the Genome
Learning Opens the Genome
Ruth Williams | Jan 17, 2018
Researchers map learning-induced chromatin alterations in mouse brain cells, and find that many affect autism-associated genes.
New Techniques Detail Embryos’ First Hours and Days
New Techniques Detail Embryos’ First Hours and Days
Jef Akst | Dec 1, 2017
New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.
Infographic: How Embryos Take Control of Their Own Development
Infographic: How Embryos Take Control of Their Own Development
Jef Akst | Nov 30, 2017
The switch from maternal factors involves dynamic reprogramming of the zygotic genome.
Image of the Day: It’s Alive
Image of the Day: It’s Alive
The Scientist Staff | Sep 13, 2017
New microscopy techniques reveal that heterochromatin—the condensed, seemingly dormant portions of DNA—is not as dense as scientists once thought.
New Technique Enables Observation of Accessible Chromatin
New Technique Enables Observation of Accessible Chromatin
Ruth Williams | Jan 1, 2017
A test tube-based genome-labeling technique has been brought under the microscope.
Infographic: Examining Open Chromatin
Infographic: Examining Open Chromatin
Ruth Williams | Dec 31, 2016
See how researchers visualize regions of active genes.
Aging Shrinks Chromosomes
Aging Shrinks Chromosomes
Ruth Williams | Feb 5, 2016
A study on human cells reveals how cellular aging affects the 3-D architecture of chromosomes.
Reveling in the Revealed
Reveling in the Revealed
Kelly Rae Chi | Jan 1, 2016
A growing toolbox for surveying the activity of entire genomes