DNA cell on scientific background
Mechanism of a Genome Packaging Machine Discovered
Detailed analyses of cohesin’s movements indicate how this protein complex hauls chromatin fibers to package DNA into loops.
Mechanism of a Genome Packaging Machine Discovered
Mechanism of a Genome Packaging Machine Discovered

Detailed analyses of cohesin’s movements indicate how this protein complex hauls chromatin fibers to package DNA into loops.

Detailed analyses of cohesin’s movements indicate how this protein complex hauls chromatin fibers to package DNA into loops.

chromatin
The hinge region of cohesin pulls DNA to two head regions, like a person’s hand-to-hand motion of pulling on a rope.
Infographic: How Genome-Packaging Protein Cohesin Handles DNA
Ruth Williams | Jan 17, 2022
The hinge region of cohesin pulls DNA to two head regions, like a person’s hand-to-hand motion of pulling on a rope.
An electron microscopy image of a cell with the nucleolus shown in blue, chromatin in green, and nuclear envelope in red
Aging in Mice Linked to Misexpression of Class of Genes
Sophie Fessl | Dec 21, 2021
Genes lacking a particular structure known as CpG islands tend to go haywire in older cells, a study finds, potentially contributing to key facets of aging. But it’s not yet clear if the relationship is causal.
VAI
Exposed: Environmental Echoes in Health - A Special Podcast Series
The Scientist Creative Services Team and Van Andel Institute
Epigenetic experts discuss how environment and diet leave lasting impressions on the human genome.
Caudipteryx Dinosaur Flock stock photo
Paleontologists Find Possible Dinosaur DNA
Chloe Tenn | Oct 26, 2021
A report of preserved fragments of nuclei and chromatin in a fossilized femur of a 125-million-year-old Caudipteryx dinosaur elicits skepticism.
Abstract illustration of DNA
Signaling Dynamics Fine-Tune Gene Expression
Ruth Williams | Sep 3, 2021
The dynamic behavior of a transcriptional activator can be used to specify the activity level of its target gene, a study suggests.
Setting High Standards for Antibody Production Using Nucleosomes
Setting High Standards for Antibody Production Using Nucleosomes
Fortis Life Sciences
A unique approach to antibody production that exposes antibody candidates to nucleosomes is revolutionizing best practices.
A microscope image of a dinoflagellate.
Dinoflagellate Genome Structure Unlike Any Other Known
Amanda Heidt | May 10, 2021
The transcription of DNA drives the remarkably tidy organization of chromosomes in the dinoflagellate Symbiodinium microadriaticum.
early-life stress, histone, chromatin, epigenetics, epigenetic modification, methylation, DNA, protein, stress, adversity, mice, genetics, genomics
Early-Life Stress Exerts Long-Lasting Effects Via Epigenome
Asher Jones | Mar 18, 2021
In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.
Sample Preparation with Single Cell Multiomics: Simultaneous Epigenomic and Transcriptomic Profiling from the Same Cell
The Scientist Creative Services Team
In this webinar brought to you by 10x Genomics, experts will discuss how to successfully prepare nuclei suspensions for Single Cell Multiome ATAC + Gene Expression experiments.
Obituary, University of Oregon, Biochemistry, Molecular Biology, chromatin, chromatin reordering, chromatin reprogramming,
Molecular Biologist Jeff McKnight Dies at 36
Amanda Heidt | Oct 8, 2020
The University of Oregon scientist studied the structure and function of chromatin, with the intent of designing new therapeutic tools.
hannah burrack entomology tobacco budworm caterpillar spotted wing Drosophila coronavirus pandemic covid-19
Amid the COVID-19 Pandemic, Some Scientists Bring the Bench Home
Emma Yasinski | May 13, 2020
PCR moves into the laundry room, while insect colonies take up residence in the shower.
Getting Started with Single Cell Multiomics: Simultaneous Epigenomic and Transcriptomic Profiling from the Same Cell
The Scientist Creative Services Team
In this webinar brought to you by 10x Genomics, experts will discuss tips for running Chromium Single Cell Multiome ATAC + Gene Expression experiments in your lab.
Image of the Day: Chromatin Forest
Emily Makowski | Jan 14, 2020
The DNA-protein complex has branches that fold back on themselves.
Cigall Kadoch Unravels Chromatin’s Role in Cancer
Chia-Yi Hou | Sep 1, 2019
The Dana-Farber Cancer Institute researcher is developing cancer therapeutics based on how the physical structure of DNA contributes to the disease.
telomere length sticky stuck chromosome aging apoptosis cancer cell oxidative stress
Image of the Day: Sticky Telomeres
Chia-Yi Hou | May 16, 2019
Telomeres in cancer cells exposed to oxidative stress got shorter and stickier.
Imaging Chromatin to Deduce Function from Form
Marissa Fessenden | Dec 1, 2018
Researchers describe their tools for probing how the physical shape of the genome affects genes’ function.
Infographic: Packing DNA
Diana Kwon | May 31, 2018
Researchers watch the protein condensin in action.
Learning Opens the Genome
Ruth Williams | Jan 17, 2018
Researchers map learning-induced chromatin alterations in mouse brain cells, and find that many affect autism-associated genes.
New Techniques Detail Embryos’ First Hours and Days
Jef Akst | Dec 1, 2017
New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.