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Aging Shrinks Chromosomes
Ruth Williams | Feb 5, 2016
A study on human cells reveals how cellular aging affects the 3-D architecture of chromosomes.
Reveling in the Revealed
Kelly Rae Chi | Jan 1, 2016
A growing toolbox for surveying the activity of entire genomes
Chromatin Conformation Computed
Anna Azvolinsky | Oct 19, 2015
By manipulating DNA sequences that guide genome-folding, researchers confirm an existing model of chromatin structure inside the nucleus.
Tracy Vence | Oct 15, 2015
A behind-the-scenes look at how researchers solved the high-resolution crystal structure of the nucleosome core particle raises the age-old question of assigning credit in science.
Kate Yandell | Dec 11, 2014
A new full-genome map indicates how DNA is folded within the nuclei of human cells.
Abby Olena | Apr 1, 2014
Researchers discover a tool to trigger an uncommon strategy cancer cells can use to lengthen their telomeres.
Karmella Haynes: Turning the Dials
Kerry Grens | Dec 1, 2013
Assistant Professor, Arizona State University. Age: 36
Loss of Potential
Dan Cossins | Jun 1, 2013
In the fruit fly, the ability of neural stem cells to make the full repertoire of neurons is regulated by the movement of key genes to the nuclear periphery.
Ed Yong | Dec 10, 2012
Archaea packages DNA around histones in a similar way to eukaryotes, suggesting that fitting a large genome into a small space was not the original role of chromatin.
How Stress is Inherited
Tia Ghose | Jul 1, 2011
Under stressful conditions, a transcription factor in flies turns on genes by releasing its hold on tightly wound DNA, a new study suggests.