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The structure of a biological cell (macro)
The Long and Winding Road to Eukaryotic Cells
Despite recent advances in the study of eukaryogenesis, much remains unresolved about the origin and evolution of the most complex domain of life.
The Long and Winding Road to Eukaryotic Cells
The Long and Winding Road to Eukaryotic Cells

Despite recent advances in the study of eukaryogenesis, much remains unresolved about the origin and evolution of the most complex domain of life.

Despite recent advances in the study of eukaryogenesis, much remains unresolved about the origin and evolution of the most complex domain of life.

nucleus
Illustration showing the path result of Eukaryogenesis
Infographic: Evolutionary Leaps Leading to Modern Eukaryotes
Amanda Heidt | Oct 17, 2022 | 2 min read
A lot happened in the hundreds of millions years separating the first and last eukaryotic common ancestors, but when and how most features arose remains a mystery.
Microscopy image of a cricket embryo, illuminated in green, pinched near one end, with one side full of bright green dots representing cell nuclei
How Wandering Nuclei Shape Developing Embryos
Viviane Callier | Jul 29, 2022 | 3 min read
As cricket blastoderms form, cell nuclei are pulled into an egg’s remaining empty space to form the new cell layers that will shape the developing animal.
Infographic showing how bursting micronuclei promote cancer
Infographic: Chromosome Errors Cause Micronuclei and Drive Cancer
Samuel F. Bakhoum | Mar 1, 2022 | 2 min read
When micronuclei rupture, chromosomes break, recombine, and form circles, causing inflammation and promoting carcinogenic growth.
Caudipteryx Dinosaur Flock stock photo
Paleontologists Find Possible Dinosaur DNA
Chloe Tenn | Oct 26, 2021 | 3 min read
A report of preserved fragments of nuclei and chromatin in a fossilized femur of a 125-million-year-old Caudipteryx dinosaur elicits skepticism.
An illustration of a yeast cell (right) and a human neuron (left) showing the processes/features that are similar in the two
Infographic: Modeling Neurodegenerative Diseases with Yeast
Mahlon Collins | Oct 1, 2021 | 3 min read
Conservation of structures and functions between single-celled fungi and human cells allow researchers to probe the brain.
Nucleus Is Key to How Cells Sense Personal Space
Abby Olena, PhD | Oct 15, 2020 | 4 min read
In two independent studies, researchers find that the organelle is responsible for a switch that allows cells to start moving when they’re squeezed.
What Paraspeckles Can Teach Us About Basic Cell Biology
Archa Fox | Dec 1, 2019 | 10+ min read
Discovering a new type of subnuclear body taught me how pursuing the unexpected can lead to new insights—in this case, about long noncoding RNAs and liquid-liquid phase separation in cells.
Infographic: How the Mitochondrial and Nuclear Genomes Interact
Viviane Callier | Nov 1, 2019 | 3 min read
From regulating each other’s gene expression to encoding different parts of the same proteins, the two genome types in every eukaryotic cell are far from independent.
The Two Genomes in Every Eukaryotic Cell
Viviane Callier | Nov 1, 2019 | 10+ min read
Interactions between mitochondrial and nuclear genomes have further-reaching effects on physiological function, adaptation, and speciation than previously appreciated.
MO infographic june the scientist
Infographic: High Precision Magnetic Tweezers
Ruth Williams | Jun 1, 2019 | 1 min read
Microscope-mounted magnets with computerized feedback control allow precision manipulations of intracellular objects.
magnetic tweezers
Intracellular Magnetic Manipulations
Ruth Williams | Jun 1, 2019 | 2 min read
Optimized tweezers enable precise 3-D manipulations of a cell’s organelles.
Image of the Day: Organ Crosstalk
Carolyn Wilke | Mar 19, 2019 | 1 min read
Zooming in on the ovarioles of Drosophila could reveal links between muscles, nutrition, and the development of eggs.
Image of the Day: Nuclei Hoarders
Carolyn Wilke | Feb 21, 2019 | 1 min read
When lacking certain enzymes that help plants coordinate cell division, Arabidopsis thaliana cells grow and collect multiple nuclei.
Infographic: Effects of Satellite DNA–Binding Proteins
Sukanya Charuchandra | Oct 1, 2018 | 1 min read
The linkers gather chromosomes together into chromocenters.
Chromosome Clusters Help Keep the Genome Together
Sukanya Charuchandra | Oct 1, 2018 | 2 min read
Without certain DNA-binding proteins, chromosomes can escape the cell nucleus.
Infographic: Packing DNA
Diana Kwon | May 31, 2018 | 1 min read
Researchers watch the protein condensin in action.
Chromosomal Instability Drives Cancer Metastasis
Jim Daley | Apr 1, 2018 | 2 min read
In the presence of cytosolic DNA, cancer cells activate antiviral pathways that disguise them as immune cells.
Infographic: How Escaped Chromosomes Can Aid Metastasis
Jim Daley | Mar 31, 2018 | 1 min read
Errors in segregation during cell division can lead to inflammation in daughter cells.
Cancer Researcher, Former AACR President Dies
Kerry Grens | Nov 13, 2017 | 2 min read
Donald Coffey, a longtime professor at Johns Hopkins University, discovered the nuclear matrix within cells and its role in DNA replication.
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