Discovering a new type of subnuclear body taught me how pursuing the unexpected can lead to new insights—in this case, about long noncoding RNAs and liquid-liquid phase separation in cells.
From regulating each other’s gene expression to encoding different parts of the same proteins, the two genome types in every eukaryotic cell are far from independent.
Interactions between mitochondrial and nuclear genomes have further-reaching effects on physiological function, adaptation, and speciation than previously appreciated.