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An illustration of a protein ribbon resting on a glossy surface.
The Journey to a Nobel Prize: A Protein Design and Structure Research Timeline
About 50 years ago, biologists set out to solve the protein-folding problem. The road to the Nobel victory has been arduous but full of small wins along the way.
The Journey to a Nobel Prize: A Protein Design and Structure Research Timeline
The Journey to a Nobel Prize: A Protein Design and Structure Research Timeline

About 50 years ago, biologists set out to solve the protein-folding problem. The road to the Nobel victory has been arduous but full of small wins along the way.

About 50 years ago, biologists set out to solve the protein-folding problem. The road to the Nobel victory has been arduous but full of small wins along the way.

protein

A gel with dye-labeled bands indicating proteins separated by electrophoresis.
SDS-PAGE Technology for the 21st Century
The Scientist Staff | Sep 2, 2024 | 2 min read
New innovations streamline and simplify SDS-PAGE from a multi-hour workflow to a matter of minutes.
Amino acid sequence presented on a computer screen as one-letter codes.
Revving the Motor: Full-Length Protein Sequencing with Nanopore Technology
Nathan Ni, PhD | Aug 12, 2024 | 4 min read
Jeff Nivala develops nanopore-based sequencing techniques to help advance proteomics. 
Discover How Protein Sequencing Evolves to Accelerate Research
The Future of Protein Sequencing
Quantum-Si | 1 min read
A new protein sequencing technology paves the way for a better understanding of protein function.
A mouse stands behind a toy table with two pieces of food on it.
A Protein-Sensing Molecular Switch Alters Facial Features
Shelby Bradford, PhD | Jun 24, 2024 | 3 min read
The mTORC1 signaling pathway senses nutritional information and influences craniofacial development in mice.
Soybeans growing against a black background.
How Do Plants Know Which Way is Up?
Hannah Thomasy, PhD | May 1, 2024 | 2 min read
Despite centuries of study, scientists still make new discoveries about the mechanisms of gravitropism.
Discover How Immunoassays Deliver Protein Biomarker Research Solutions
Protein Biomarker Research Solutions
The Scientist Creative Services Team in collaboration with MilliporeSigma | 1 min read
Immunoassays help researchers across a range of applications from screening to targeted analysis.
A photo of the PlatinumTM Next-Generation Protein Sequencer, a small roughly cube-shaped blue-black-silver instrument.
Breaking Down Barriers to Protein Sequencing
The Scientist Staff | Sep 1, 2023 | 2 min read
Next-generation protein sequencing is becoming more powerful, streamlined, and accessible. 
Image of the fly brain (grey) highlighting the population of neurons (pink) to which the gut-secreted peptide CCHa1 signals
A Protein-Rich Diet Helps Mice and Flies Sleep More Soundly: Study
Alejandra Manjarrez, PhD | Mar 24, 2023 | 3 min read
The effect appears to be mediated by a gut-secreted peptide that signals to neurons in the brain that modulate the response to mechanical vibrations.
Twist
Synthetic Screens, Genes, and De Novo Proteins - A Special Podcast Series
The Scientist and Twist Bioscience | 2 min read
In this podcast series, scientists discuss the unique ways they employ synthesized DNA libraries in their research. 
2022 Top 10 Innovations 
2022 Top 10 Innovations
The Scientist | Dec 12, 2022 | 10+ min read
This year’s crop of winning products features many with a clinical focus and others that represent significant advances in sequencing, single-cell analysis, and more.
A false color transmission electron microscope micrograph showing the nuclear envelope, the rough endoplasmic reticulum, the nucleus, and the cytoplasm.
New Gene Mutants Identified in Rare Motor Neuron Diseases
Clare Watson | Oct 17, 2022 | 2 min read
The discovery of gene variants in cases of hereditary spastic dysplasia could provide a diagnosis to affected families where no genetic cause could be found before.
A Comprehensive Guide to Proteomics
What Is Proteomics?
Sejal Davla, PhD | 6 min read
Explore proteomics concepts, approaches, and data analysis.
Illustration of blue and gray amino acids loosely forming protein
Fungal Cold Adaptation Linked to Protein Structure Changes: Study
Patience Asanga | Sep 20, 2022 | 4 min read
Environmental pressure seems to spawn changes in the intrinsically disordered regions of enzymes in polar yeasts, allowing them to adapt to extreme cold.
Infographic showing how neurodegenerative diseases have long been associated with aggregations of apparently toxic proteins
Infographic: Secret Lives of Neurodegeneration-Linked Proteins
Catherine Offord | Aug 1, 2022 | 5 min read
Maligned peptides such as the Alzheimer’s-associated amyloid precursor protein may have critical roles in the healthy brain.
Using Mass Photometry to Assess and Characterize Protein Samples 
Rapidly Characterizing Complex Samples With Mass Photometry
The Scientist | 1 min read
In this webinar, Perla Vega and Philip Kitchen will explore how scientists can use mass photometry to assess sample quality and characterize proteins.
The fossil tooth found in the Annamite Mountains in Laos
Ancient Tooth Could Be Clue in Denisovan Migration Mystery
Andy Carstens | May 18, 2022 | 2 min read
The new fossil from Laos helps answer the question of how some people from Oceania carry DNA from the ancient hominin.
Infographic about SLiMs in SARS-CoV-2 Infection
Infographic: Short Protein Motifs’ Role in SARS-CoV-2 Infection
Conchita Fraguas Bringas and Jakob Nilsson | May 16, 2022 | 4 min read
Known as SLiMs, these stretches of up to 10 amino acids play notable roles in cell biology, including responses to viral invasion.
Discover How CF® Dyes Let Scientists Delve Deeper into Biological Phenomena
CF® Dyes: Clearer Fluorescent Results
Biotium | 1 min read
CF®  Dyes combine pegylation and sulfonation to create fluorescent dyes with better signal intensity, more solubility, and superior specificity.
Conceptual image of coronavirus, SARS?Cov?2 infects a human cell
Viruses Target Super-Short Protein Motifs to Disrupt Host Biology
Conchita Fraguas Bringas and Jakob Nilsson | May 16, 2022 | 10+ min read
Only recently appreciated as critical components of cellular functions, unstructured stretches of amino acids called SLiMs are key to viral-host interactions.
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