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Infographic: What is ME/CFS?

The COVID-19 pandemic is sparking renewed efforts to study the underlying causes of this complex, debilitating disease, which might be triggered by the novel coronavirus.

Written byKatarina Zimmer
| 10 min read

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People with myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) suffer from a chronic, debilitating fatigue that can leave them unable to maintain a job or take part in normal activities. Because of the condition’s unclear pathology and root causes, the disease was long dismissed as a psychiatric illness by doctors and ignored by researchers. Today, it’s estimated that 836,000 to 2.5 million Americans suffer from the disease—the vast majority of them undiagnosed—and that the illness costs billions annually in medical bills and lost incomes.

Below are the diagnostic criteria for the disease, according to the National Academy of Medicine.

ME/CFS patients typically recall a sudden onset of a profound fatigue that lasts longer than six months and significantly reduces their ability to engage in normal activities.

The hallmark of the condition is a worsening of symptoms 12–48 hours after physical or mental activity, which can leave patients ...

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Meet the Author

  • katya katarina zimmer

    After a year teaching an algorithm to differentiate between the echolocation calls of different bat species, Katarina decided she was simply too greedy to focus on one field of science and wanted to write about all of them. Following an internship with The Scientist in 2017, she’s been happily freelancing for a number of publications, covering everything from climate change to oncology. Katarina is a news correspondent for The Scientist and contributes occasional features to the magazine. Find her on Twitter @katarinazimmer and read her work on her website.

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