Kawasaki Disease a Wind-borne Malady

Cases of the debilitating childhood disease in Japan are likely caused by toxins that float in from China’s farmlands, a study finds.

Written byRina Shaikh-Lesko
| 1 min read

Register for free to listen to this article
Listen with Speechify
0:00
1:00
Share

WIKIMEDIA, CHEVY111Kawasaki disease, the number-one cause of acquired heart disease in children in industrialized countries, may be caused by toxins that arrive with seasonal winds, according to a study published this week (May 19) in PNAS. A team led by Xavier Rodó, a climate scientist at the Institut Català de Ciències del Clima (IC3) in Barcelona, Spain, studied outbreaks of the disease in Japan from 1979 to 2010. Comparing that information to wind patterns, the researchers narrowed the source of the disease to farmland in northeastern China.

The researchers ruled out infectious agents because of the quick onset of the short incubation period they calculated. Whether the causative toxin is a fungus, pesticide, or plant-based remains to be seen. The team also found Candida fungus in air samples taken from winds blowing from northeastern China. “I think there is evidence that [Kawasaki disease] looks like other bacterial toxin diseases,” Samuel Dominguez, a pediatric infectious-disease specialist at the University of Colorado School of Medicine who was not involved in the study, told Nature News.

Kawasaki disease is most common in children under five and causes a rash and an often uncontrollable fever. The disease was first identified in Japan in 1961, but its cause remains a mystery. The highest incidence of Kawasaki disease ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

Share
July Digest 2025
July 2025, Issue 1

What Causes an Earworm?

Memory-enhancing neural networks may also drive involuntary musical loops in the brain.

View this Issue
Accelerating Recombinase Reprogramming with Machine Learning

Accelerating Recombinase Reprogramming with Machine Learning

Genome Modeling and Design: From the Molecular to Genome Scale

Genome Modeling and Design: From the Molecular to Genome Scale

Twist Bio 
Screening 3D Brain Cell Cultures for Drug Discovery

Screening 3D Brain Cell Cultures for Drug Discovery

DNA and pills, conceptual illustration of the relationship between genetics and therapeutic development

Multiplexing PCR Technologies for Biopharmaceutical Research

Thermo Fisher Logo

Products

waters-logo

Waters and BD's Biosciences & Diagnostic Solutions Business to Combine, Creating a Life Science and Diagnostics Leader Focused on Regulated, High-Volume Testing

zymo-research-logo

Zymo Research Partners with Harvard University to Bring the BioFestival to Cambridge, Empowering World-class Research

10x-genomics-logo

10x Genomics and A*STAR Genome Institute of Singapore Launch TISHUMAP Study to Advance AI-Driven Drug Target Discovery

The Scientist Placeholder Image

Sino Biological Sets New Industry Standard with ProPure Endotoxin-Free Proteins made in the USA