Kawasaki Disease a Wind-borne Malady

Cases of the debilitating childhood disease in Japan are likely caused by toxins that float in from China’s farmlands, a study finds.

Written byRina Shaikh-Lesko
| 1 min read

Register for free to listen to this article
Listen with Speechify
0:00
1:00
Share

WIKIMEDIA, CHEVY111Kawasaki disease, the number-one cause of acquired heart disease in children in industrialized countries, may be caused by toxins that arrive with seasonal winds, according to a study published this week (May 19) in PNAS. A team led by Xavier Rodó, a climate scientist at the Institut Català de Ciències del Clima (IC3) in Barcelona, Spain, studied outbreaks of the disease in Japan from 1979 to 2010. Comparing that information to wind patterns, the researchers narrowed the source of the disease to farmland in northeastern China.

The researchers ruled out infectious agents because of the quick onset of the short incubation period they calculated. Whether the causative toxin is a fungus, pesticide, or plant-based remains to be seen. The team also found Candida fungus in air samples taken from winds blowing from northeastern China. “I think there is evidence that [Kawasaki disease] looks like other bacterial toxin diseases,” Samuel Dominguez, a pediatric infectious-disease specialist at the University of Colorado School of Medicine who was not involved in the study, told Nature News.

Kawasaki disease is most common in children under five and causes a rash and an often uncontrollable fever. The disease was first identified in Japan in 1961, but its cause remains a mystery. The highest incidence of Kawasaki disease ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies