Keys to the Minibar

Degraded DNA from museum specimens, scat, and other sources has thwarted barcoding efforts, but researchers are filling in the gaps with mini-versions of characteristic genomic stretches.

Written byKerry Grens
| 4 min read

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OLD BAT: Specimens from museum collections, such as this bat collected in 1923, present challenges to barcoding because their DNA can be badly degraded.COURTESY OF ELIZABETH L. CLARE

Specimen collectors from days of yore did not always handle their catch with care, at least not when it came to preserving DNA. You can’t blame them, of course. DNA as genetic material wasn’t even a twinkle in the scientific community’s eye a century ago. Aquatic specimens were often preserved in alcohol or formalin, making it all but impossible to extract usable DNA for barcoding analysis, a standard method of identifying species by variations in the same gene. Even among dry-preserved specimens, DNA breaks down fairly quickly, dissuading many barcoders from working with museum collections—with the result that they miss out on museums’ wealth of species information.

“Collections are the best places in the world to go collecting for biodiversity,” says Paul Hebert, a barcoding ...

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  • kerry grens

    Kerry served as The Scientist’s news director until 2021. Before joining The Scientist in 2013, she was a stringer for Reuters Health, the senior health and science reporter at WHYY in Philadelphia, and the health and science reporter at New Hampshire Public Radio. Kerry got her start in journalism as a AAAS Mass Media fellow at KUNC in Colorado. She has a master’s in biological sciences from Stanford University and a biology degree from Loyola University Chicago.

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