Features

Viruses Reconsidered

A Twist of Fate
Capsule Reviews

Capsule Reviews
The Sixth Extinction, Joy, Guilt, Anger, Love, Ha! The Science of When we Laugh and Why, and Ten Thousand Birds
Bio Business

Incubator Boom
From San Francisco to St. Louis, biotech incubators are proliferating across North America. Can they deliver on their promise of fueling the economy?
Lab Tools

A CRISPR Fore-Cas-t
A newcomer’s guide to the hottest gene-editing tool on the block

Keeping Your Cool
A guide to recent advances in ultra-low-temperature freezers and accessories that can help safeguard frozen samples
Modus Operandi

Tension Tracker
For the first time, researchers quantify the mechanical forces cells exert on one another.
The Literature

Path Finding
Biochemistry reveals the missing link in a pathway that archaea and some bacteria use to generate essential compounds.

Exosome Tentacles
Unlike the usual smooth, spherical shape of exosomes, glioblastoma-derived exosomes appear to have long nanofilaments protruding from their surfaces.

Early Evidence
Fossilized structures suggest that mat-forming microbes have been around for almost 3.5 billion years.
Profiles

Summoned From the Depths
Geobiologist Roger Summons analyzes organic material in rocks found deep inside Earth, looking for evidence of how life originated and evolved on our planet—and possibly on Mars.
Scientist to Watch

Matthew Powner: Origin Solver
Lecturer, Department of Chemistry, University College London. Age: 32
Reading Frames

Is Earth Special?
Reconsidering the uniqueness of life on our planet
Foundations

Discovering Archaea, 1977
Ribosomal RNA fingerprints reveal the three domains of life.
Critic at Large

Campus Considerations
Career options and research opportunities at two-year colleges are often underappreciated.
Thought Experiment

Ancient Life in the Information Age
What can bioinformatics and systems biology tell us about the ancestor of all living things?
Notebook

Northern Exposure
Researchers are using snowdrifts to artificially warm Arctic tundra during winter and finding that more carbon is released from the soil than plants can soak up from the atmosphere.

Air Traffic
Scientists use DNA sequencing to identify what’s attracting birds to airports, where midair collisions with planes can be devastating.

Jaws, Reconsidered
Biologist Jelle Atema is putting the sensory capabilities of sharks to the test—and finding that the truth is more fascinating than fiction.

Keys to the Minibar
Degraded DNA from museum specimens, scat, and other sources has thwarted barcoding efforts, but researchers are filling in the gaps with mini-versions of characteristic genomic stretches.
Speaking of Science

Speaking of Science
March 2014's selection of notable quotes
Editorial

Let There Be Life
How did Earth become biological?
Contributors

Contributors
Meet some of the people featured in the March 2014 issue of The Scientist.
Cover Story

RNA World 2.0
Most scientists believe that ribonucleic acid played a key role in the origin of life on Earth, but the versatile molecule isn’t the whole story.