Lungfish Cocoon: A Living Barrier Against Infection During Estivation

Researchers find that the protective outer layer that lungfish make to survive extended dry periods—once thought to be a simple mucus shell—contains immune cells that trap bacteria and protect the animals from infection.

Written byAbby Olena, PhD
Published Updated 4 min read
The lungfish has a beige face and grey spotted body with a darker tail fin, as well as four long, spindly appendages. It is on a white background.
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African lungfish (Protopterus spp.) live in water for part of each year. During yearly dry seasons, though, they dig into mud, curl up, and secrete staggering amounts of mucus that then hardens to form a cocoon of protection. This process, known as estivation, allows the animals to survive on land for years, protecting them from complete desiccation until water returns, at which point they rehydrate their bodies and go back to swimming. Most scientists believed the cocoon to be inert, but a study in Science Advances suggests otherwise. The authors found that the mucus cocoon is filled with white blood cells called granulocytes, which create extracellular traps to nab bacteria and protect the animals from sepsis, skin infections, and blood loss.

“This is an animal that, for this brief moment in time, can—like a force field—extend its body, its actual living body beyond its scope,” says Ashley Poust, a vertebrate ...

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Meet the Author

  • abby olena

    As a freelancer for The Scientist, Abby reports on new developments in life science for the website. She has a PhD from Vanderbilt University and got her start in science journalism as the Chicago Tribune’s AAAS Mass Media Fellow in 2013. Following a stint as an intern for The Scientist, Abby was a postdoc in science communication at Duke University, where she developed and taught courses to help scientists share their research. In addition to her work as a science journalist, she leads science writing and communication workshops and co-produces a conversational podcast. She is based in Alabama.  

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