IgA antibodies appear to bind to specific species of commensal gut bacteria in mice, according to a study.

Several lines of evidence suggest that targeting the body’s defense pathways might help treat a subset of people with the psychiatric disorder. But many open questions remain.

Scientists have pinpointed several pathways through which the immune system could disrupt neuronal functioning and thereby lead to psychotic symptoms.

Two recent papers provide insight into possible risk factors for developing the chronic condition, including autoantibodies and diabetes.

Immunologists and parasitologists are working to revive the idea that helminths, and more specifically the molecules they secrete, could help treat allergies and autoimmune disease.

Research in animals and people supports a range of mechanisms by which the parasites affect physiology and immune responses.

Researchers report what appears to be the second case of a person’s immune system clearing the virus on its own.

Researchers find that the protective outer layer that lungfish make to survive extended dry periods—once thought to be a simple mucus shell—contains immune cells that trap bacteria and protect the animals from infection.

The Northwestern University researcher studies how adaptive immune cells influence neurodegenerative disease.

The achievement bolsters hopes that nonhuman animals could be used to remedy the shortage of transplantable organs.

The microbiota helps align a mouse’s innate immune system with its feeding patterns, prepping the animal to fend off infection when it’s most likely to be eating.

Four dozen children with severe combined immunodeficiency (SCID) who received a corrective gene carried by a virus have working immune systems two to three years later, according to three independent clinical trials.

In a new study, human and mouse cells recognized only one in five bacterial species collected from more than a mile below the Pacific Ocean’s surface.