
Features
Modus Operandi

Synthetic Organelles Let Researchers Control Cell Behavior
A technique that reversibly bundles tagged cargo into artificial membraneless compartments gives scientists the ability to switch cell processes on and off.
Infographics

Infographic: One Way to Flip the Cell Behavior Switch
Engineered cells produce proteins that allow scientists to turn cellular processes on and off.

Infographic: Enhancer Activity Across the Tree of Life
Scientists are still trying to paint a complete picture, but it’s clear that these gene expression regulators have an unusual evolutionary history.

Infographic: Animal Embryos Coopt Sound to Survive and Thrive
Across the tree of life, animals use sound and other vibrations to glean valuable sensory information about their environments even before they are born.
The Literature

Epithelial Cell Signaling Helps Maintain Tissue Integrity
Using a transgenic fruit fly model, researchers demonstrate how epithelial barriers are maintained in living organisms despite high levels of cell turnover and death.

Contrary to Common Belief, Some Older Trees Make Fewer Seeds
An analysis of more than half a million trees reveals that many species begin to taper off seed production once they hit a certain size.
Foundations

An Earthy-Smelling Substance, 1964
How the pungent odor that occurs after a light rain became a well-studied phenomenon
Scientist to Watch

David Gate Probes Links Between Alzheimer’s and the Immune System
The Northwestern University researcher studies how adaptive immune cells influence neurodegenerative disease.
Notebook

Milky Seas Can Be Spotted from Space
Analysis of data from a new satellite sensor helps researchers detect large patches of bioluminescence in the oceans faster than ever before.

Ubiquitous Little Earthworms Might Have Got Around on Driftwood
Researchers also tried placing the worms on pigeons as part of a study aiming to uncover how the tiny invertebrates ended up all around the world.
Reading Frames

Opinion: Being, Feeling, and Knowing: Our Path to Consciousness
The idea that minds and consciousness might be generated by the nervous system alone is false.
Critic at Large

Opinion: The Problem with Preprints
Preprints can be valuable additions to the scientific literature. But we must start seeing them as perishable commodities rather than akin to peer-reviewed, published studies.
Careers

How Brexit Is Transforming the UK’s STEM Community
Scientists face the ramifications of the country’s departure from the European Union, from delays in laboratory supplies to difficulties hiring international students and faculty.
Speaking of Science

Ten Minute Sabbatical
Take a break from the bench to puzzle and peruse.
Editorial

Brave New Publishing World
Preprints are likely here to stay. The press, the public, and the research community must adapt to this relatively recent model of scientific publishing if we are to extract its benefits while avoiding its pitfalls.