David Gate Probes Links Between Alzheimer’s and the Immune System

The Northwestern University researcher studies how adaptive immune cells influence neurodegenerative disease.

james m gaines
| 4 min read
Microscopic photograph of brain tissue demonstrating the characteristics of Alzheimer's disease

Register for free to listen to this article
Listen with Speechify
0:00
4:00
Share

ABOVE: David Gate studies links between the immune system and Alzheimer's, a disease characterized by amyloid-β plaques in the brain, seen in this micrograph as lightly-colored circles.
© ISTOCK.COM, OGPHOTO

For David Gate, one of the first real litmus tests of whether a research career was for him came while dissecting retinas as a premed student studying psychology at the University of California, Santa Barbara. Working in the eye biology lab didn’t really capture his imagination, and parts of the work were tedious, but Gate says that despite that, he loved the process—the basic work of doing experiments. “I quickly became a lab rat all day and night,” and was soon dissecting retinas better than anyone in the lab, Gate tells The Scientist.

After graduating in 2007, Gate went on to work as a lab technician with immunologist and Alzheimer’s disease researcher Terrence Town at Cedars-Sinai Hospital in Los Angeles. The ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here

Keywords

Meet the Author

  • james m gaines

    James M. Gaines

    James Gaines is a freelance science journalist in Seattle, Washington. He got his start at City University in London, where he received a master's degree in science journalism. Since then, his writing has appeared in outlets such as Nature, Undark, Atlas Obscura, and Knowable Magazine. He also works as a fact-checker and a regular contributor to the YouTube channel SciShow. He once had an alligator snapping turtle as a pet for about two hours.

Published In

November cover of The Scientist
November 2021

Embryonic Eavesdropping

Animals start listening even before they enter the world

Share
A greyscale image of cells dividing.
March 2025, Issue 1

How Do Embryos Know How Fast to Develop

In mammals, intracellular clocks begin to tick within days of fertilization.

View this Issue
Discover the history, mechanics, and potential of PCR.

Become a PCR Pro

Integra Logo
Explore polypharmacology’s beneficial role in target-based drug discovery

Embracing Polypharmacology for Multipurpose Drug Targeting

Fortis Life Sciences
3D rendered cross section of influenza viruses, showing surface proteins on the outside and single stranded RNA inside the virus

Genetic Insights Break Infectious Pathogen Barriers

Thermo Fisher Logo
A photo of sample storage boxes in an ultra-low temperature freezer.

Navigating Cold Storage Solutions

PHCbi logo 

Products

The Scientist Placeholder Image

Gilead’s Capsid Revolution Meets Our Capsid Solutions: Sino Biological – Engineering the Tools to Outsmart HIV

Stirling Ultracold

Meet the Upright ULT Built for Faster Recovery - Stirling VAULT100™

Stirling Ultracold logo
Chemidoc

ChemiDoc Go Imaging System ​

Bio-Rad
The Scientist Placeholder Image

Evotec Announces Key Progress in Neuroscience Collaboration with Bristol Myers Squibb