Image of a 3D human brain with colorful synapses.

| 4 min read

First-of-Its-Kind Egyptian Multiomics Dataset Aims to Advance Dementia Research

A global research initiative led by the Davos Alzheimer’s Collaborative seeks to bridge research gaps by broadening representation through diverse and inclusive data.

Light microscopy micrograph of human cerebral cortex neurons showing dense neurofibrillary tangle content that is characteristic of neuropathology and frequently seen in the tauopathies.

| 8 min read

Tau Protein Function and Disease Roles

| 4 min read

Study Reveals a Link Between Herpes Virus, Head Injuries, and Alzheimer’s Disease

Alzheimer's Disease

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Uncovering the Unexpected: Developing a Novel Anti-Tau Therapy

Charlene Lancaster, PhD | | 4 min read

A 3D artist’s rendition of a macrophage.

What Drives Myeloid Cell Responses to Disease

Bio X CellandThe Scientist | | 4 min read

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AI-Assisted Genome Studies Are Riddled with Errors

Sahana Sitaraman, PhD | | 3 min read

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Unlocking the Metabolic Drivers of Alzheimer’s Disease

| 2 min read

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The Unexplored Effects of Weight-Loss Drugs on the Brain

Sahana Sitaraman, PhD | | 4 min read

Neurons with neurofibrillary tangles made of tau protein and amyloid-beta plaque.

Neurodegenerative Disease Markers and Detection Methods

The Scientist | | 1 min read

An illustration of neurons surrounded by protein aggregates.

Accelerating Protein Aggregation Analysis

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Gut Microbe Metabolites Lower Levels of Toxic Tau

Kamal Nahas, PhD | | 5 min read

Bringing Gene Therapy to the Brain

Bringing Gene Therapy to the Brain

Available on Demand

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Developing Homogenous 3D Neural Cultures for High Throughput Screening

Niki Spahich, PhD | | 3 min read

<em >The Scientist</em>’s Journal Club: Neuroscience and Cell Biology

The Scientist’s Journal Club: Neuroscience and Cell Biology

Available on Demand

You Are When You Eat

Iris Kulbatski, PhD | | 3 min read

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A Rare Genetic Mutation Protects Against Alzheimer's Disease

Hannah ThomasyandDrug Discovery News | | 4 min read

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Science Summarized: The Mosaic Brain

The Scientist | | 1 min read

TSS

Immune Cells and ALS: A Balance Between Life and Death

The Scientist | | 1 min read

Microglia stained black

Opinion: Harnessing Microglia Cells to Stave Off Neurodegeneration

Kristine ZengelerandThe Conversation | | 5 min read

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A Gene Variant Linked to Alzheimer’s May Disrupt Myelin Production

Andy Carstens | | 5 min read

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Opinion: Science Needs Better Fraud Detection—And More Whistleblowers

Aman MajmudarandUndark | | 5 min read

a false color transmission electron microscope image of a neuronal cell body, with lysosomes colored dark green

Scientists Uncover Major Pathway Cells Use to Mend Leaky Lysosomes

Holly Barker, PhD | | 3 min read

Learn about effective biomarker detection from the blood

Next-Level Neuroscience

MilliporeSigmaandThe Scientist | | 1 min read

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Image of Atul Butte.

Biomedical Informatician Atul Butte Dies at 55

Atul Butte mined big data to fuel biomedical insights to advance precision medicine.

An illustration showing the accumulation of amyloid plaques between nerve cells, which is the underlying cause of disorders like Alzheimer’s and Parkinson’s disease.

A Gut Pathogen’s Unexpected Weapon Against Amyloid Diseases

A protein from Helicobacter pylori inhibits amyloid formation in both microbes and humans, offering new leads for antimicrobial and neurodegenerative disease therapies.

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

A series of rodent experiments showed that even with abundant food and water, personal space is essential to prevent societal collapse, but Universe 25's relevance to humans remains disputed.

Two domesticated animals, a red border collie dog and horse together at sunset.

The Genes That Shaped Pets and Domesticated Livestock

Comparative genomics revealed genetic differences between wild and domestic animals, highlighting traits influenced by human selection.

Multimedia

Explore synthetic DNA’s many applications in cancer research

Weaving the Fabric of Cancer Research with Synthetic DNA

Modern DNA synthesis platforms empower researchers to explore the molecular world, from next-generation sequencing to cell and gene therapy development.

Two images of U2OS cells transfected with a fluorescently labeled protein. The left panel shows AI-based analysis of transfection efficiency, with cells bounded in yellow and label marked in magenta. The right panel shows baseline fluorescence.

Leveraging AI for Analyzing Cell Transfection Efficiency

Explore how AI can provide more accurate and reliable measurements of transfection success rate.

Image of small blue creatures called Nergals. Some have hearts above their heads, which signify friendship. There is one Nergal who is sneezing and losing health, which is denoted by minus one signs floating around it.

June 2025, Issue 1

Nergal Networks: Where Friendship Meets Infection

A citizen science game explores how social choices and networks can influence how an illness moves through a population.

View this Issue

Research Resources

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Explore synthetic DNA’s many applications in cancer research

Weaving the Fabric of Cancer Research with Synthetic DNA

Modern DNA synthesis platforms empower researchers to explore the molecular world, from next-generation sequencing to cell and gene therapy development.

Illustrated plasmids in bright fluorescent colors

Enhancing Elution of Plasmid DNA

An improved chromatography membrane elution method helps scientists achieve higher yields of pure plasmid DNA.

An illustration of green lentiviral particles.

Maximizing Lentivirus Recovery

By fine-tuning polishing conditions, scientists attain high titers of infectious lentiviral particles during purification.

Explore new strategies for improving plasmid DNA manufacturing workflows.

Overcoming Obstacles in Plasmid DNA Manufacturing

Discover a scalable and flexible GMP-compliant workflow for producing plasmid DNA.

Products

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Waters Enhances Alliance iS HPLC System Software, Setting a New Standard for End-to-End Traceability and Data Integrity

Industry-first smart HPLC system to provide authenticated user access verification on onboard touchscreen for superior security.

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Agilent Unveils the Next Generation in LC-Mass Detection: The InfinityLab Pro iQ Series

Setting new standards for intelligent mass detection, sensitivity, and sustainability.

Agilent Announces the Enhanced 8850 Gas Chromatograph

Compact, Powerful, and now Mass Spec-Connected for Superior Analytical Performance

Pioneering Cancer Plasticity Atlas will help Predict Response to Cancer Therapies

The Wellcome Sanger Institute, Helmholtz Munich, and Parse Biosciences have announced a landmark international collaboration to create a Cancer Plasticity Atlas.