Red Blood Cells Activate Innate Immune System
Red Blood Cells Activate Innate Immune System
Researchers link the ability of the cells to bind and present DNA from pathogens and cell death to anemia, which is common in COVID-19, and immune activation.
Red Blood Cells Activate Innate Immune System
Red Blood Cells Activate Innate Immune System

Researchers link the ability of the cells to bind and present DNA from pathogens and cell death to anemia, which is common in COVID-19, and immune activation.

Researchers link the ability of the cells to bind and present DNA from pathogens and cell death to anemia, which is common in COVID-19, and immune activation.

immune cells
Microglia as Therapeutic Targets in Neurodegenerative Diseases
Microglia as Therapeutic Targets in Neurodegenerative Diseases
Sruthi S. Balakrishnan | Oct 1, 2021
Pharmaceutical companies ramp up efforts to get the brain’s immune cells to help treat Alzheimer’s disease and other conditions, but not everyone agrees the approach will be effective.
Stress Paralyzes Immune Cells
Stress Paralyzes Immune Cells
Emma Yasinski | Jul 1, 2021
Scientists show that an influx of noradrenaline can halt immune cells in mice.
Mucosal Vaccines Protect Mice from Viruses, Cancer
Mucosal Vaccines Protect Mice from Viruses, Cancer
Emma Yasinski | Jun 1, 2021
Scientists use a protein found in mucus membranes to ferry vaccines to the lymph nodes.
CAR Macrophages Tackle Challenges in Solid Cancer Treatment
CAR Macrophages Tackle Challenges in Solid Cancer Treatment
Amanda Heidt | Mar 26, 2021
Following on the success of CAR T cells used to treat cancers of the blood, researchers have launched a Phase 1 clinical trial of genetically modified macrophages to target solid tumors.
COVID-19 Vaccine Combos Aim to Boost Immunity
COVID-19 Vaccine Combos Aim to Boost Immunity
Asher Jones | Mar 9, 2021
Mix-and-match shots could simplify vaccine rollout and stimulate more-robust immune responses. Ongoing clinical trials will soon give answers.
Immunotherapy Combo Reduces Solid Tumors in Mice
Immunotherapy Combo Reduces Solid Tumors in Mice
Amanda Heidt | Sep 9, 2020
When tumor cells are infected with an oncolytic virus carrying a modified CD19 gene, they become targets for CAR T cells engineered to recognize this molecular marker.
Blood Replacement Rescues Mice from Stroke Damage
Blood Replacement Rescues Mice from Stroke Damage
Amanda Heidt | Aug 31, 2020
When mice that had suffered a stroke were given blood from a healthy donor, they experienced less tissue and neurological damage.
SARS-CoV-2-Reactive T Cells Found in Patients with Severe COVID-19
SARS-CoV-2-Reactive T Cells Found in Patients with Severe COVID-19
Abby Olena | Jul 3, 2020
A small subset of uninfected people also had SARS-CoV-2-fighting T cells, a finding that scientists are still trying to figure out.
How Immune Cells Make the Brain Forget
How Immune Cells Make the Brain Forget
Ashley Yeager | May 1, 2020
Microglia ingest nerve cell connections, leading to the loss of information stored in neuronal circuits.
Could Curbing Runaway Immune Responses Treat COVID-19?
Could Curbing Runaway Immune Responses Treat COVID-19?
Shawna Williams | Apr 21, 2020
Drugs targeting patients’ immune systems, rather than the virus itself, could be key to recovery from severe cases of the disease, some researchers suggest.
Image of the Day: Memory Erasure
Image of the Day: Memory Erasure
Amy Schleunes | Feb 12, 2020
By trimming synapses in the adult mouse hippocampus, microglia help facilitate forgetting.
CRISPR-Edited Cells for Cancer Therapy Safe in Humans: Trial
CRISPR-Edited Cells for Cancer Therapy Safe in Humans: Trial
Ashley Yeager | Feb 6, 2020
In the first clinical study of its kind in the US, researchers used CRISPR to modify CAR T cells to make them more potent against cancer, but the clinical benefits are unknown.
Excess of Immune Cells Found in Brains of People with Autism
Excess of Immune Cells Found in Brains of People with Autism
Ashley Yeager | Jan 13, 2020
An accumulation of T cells and astrocytes in postmortem brain tissue hints at possible autoimmune origins for many cases of autism.