Katie McKenna discusses a combination CAR T and viral therapy that kills solid tumors.

Alessandro Sette and Shane Crotty discuss the T cell response to SARS-CoV-2 and the implications for vaccine design and robust immune memory.

The rare complication known as multisystem inflammatory syndrome in children (MIS-C) differs from both Kawasaki disease and severe adult cases of COVID-19, a study finds.

Scientists are examining the role of T cells, which are likely crucial for long-term protection against SARS-CoV-2.

A rogue hybrid lymphocyte, bearing characteristics of both B and T cells, may play a role in driving autoimmunity in the disease, although the mechanism is far from clear.

Human natural killer cells, previously considered not to participate in adaptive immunity, remember viral antigens after initial exposures, according to a new study.

The transcriptional regulator dampens the immune system’s ability to elicit an antitumor response, a study shows.

The immune system tolerates the colonization of commensal bacteria on the skin with the aid of regulatory T cells during the first few weeks of life, a mouse study shows.

When influenza invades the mouse respiratory tract, neutrophils guide the subsequent T-cell attack on infected tissue, scientists show.  

Researchers find evidence that measles vaccines reduced deaths from other infectious diseases due to “immune amnesia.”

A census of adaptive immune system components in human skin reveals a variety of resident and traveling memory T cells.

Sequencing cells from human fetal blood samples, researchers track the development of the adaptive immune system throughout gestation.   

B and T cells may be the memory masters of the immune system, but research reveals that other cells can be primed by pathogens, too.

In the evolutionary arms race between pathogens and hosts, genetic elements known as transposons are regularly recruited as assault weapons for cellular defense.

Regulation of genome expression orchestrates the behavior of insect castes and the human response to social stress.

Researchers uncover a group of mobile genetic elements in bacteria and archaea encoding a Cas enzyme.

Researchers show that vitamin A deficiency can help protect mice against parasitic worm infections.

Scientists show that mice housed at room temperature are less able to fight tumors.

Protein interaction networks in Arabidopsis give clues to plant evolution and immunity.