Features

The Enigmatic Membrane
Muriel Mari, Sharon A. Tooze, and Fulvio Reggiori | Feb 1, 2012
Despite years of research, the longstanding mystery of where the autophagosome gets its double lipid bilayers is not much clearer.
The War Within
Ole H. Petersen, Oleg V. Gerasimenko, and Julia V. Gerasimenko | Feb 1, 2012
Unraveling the molecular causes of acute pancreatitis—a potentially deadly disease in which the pancreas essentially digests itself—is yielding clues to how it might be treated.
Casting a Wide Eye
Cristina Luiggi | Feb 1, 2012
Scientists study a variety of large-scale biological phenomena from the vantage point of space.

Editorial

On the Menu

On the Menu

Digestion on the cellular level: two mysteries examined

Speaking of Science

Speaking of Science

Speaking of Science

February 2012's selection of notable quotes

Notebook

Genghis Jon

Genghis Jon

By helping Mongolians cultivate an understanding of their native insect fauna, scientists hope to protect the country's unique yet fragile ecosystems.

Sweet and Sour Science

Sweet and Sour Science

Japanese researchers unravel the mystery of miracle fruit.

Science Afield

Science Afield

Portable wet-lab kits allow even soldiers stationed in war zones to earn college science credits.

Reading Tea Leaves

Reading Tea Leaves

Cyclic peptides, discovered in an African tea used to speed labor and delivery, may hold potential as drug-stabilizing scaffolds, antibiotics, and anticancer drugs.

Thought Experiment

Ready for Prime Time

Ready for Prime Time

Ready for Prime Time

Biomarkers of Alzheimer’s disease are ready for widespread use in clinical trials.

Critic at Large

Never Say Never

Never Say Never

Novel observations can sometimes be correct for unexpected reasons.

Learning by Doing

Learning by Doing

Having freshmen perform research doesn’t just improve undergraduate learning, it convinces more students to become science majors.

Modus Operandi

Switching the Bait

Switching the Bait

Turning a standard technique into an unbiased screen for diagnostic biomarkers

The Literature

Forced Feeding

Forced Feeding

Editor's choice in drug development

Immune Heat

Immune Heat

Editor's choice in immunology

Give Me a Hug

Give Me a Hug

Editor's choice in cell biology

Scientist to Watch

Rommie Amaro: Protein Explorer

Rommie Amaro: Protein Explorer

Assistant Professor, Department of Chemistry and Biochemistry University of California, San Diego. Age: 34

Lab Tools

Little Squirts

Little Squirts

A road map to liquid-handling solutions on the market

Careers

Female Frontrunners

Female Frontrunners

How to successfully surmount the challenges women face in becoming biotech industry leaders

Reading Frames

Killing with Kindness

Killing with Kindness

Killing with Kindness

Studying the evolution of altruistic behaviors reveals how knee-jerk good intentions can backfire.

Foundations

Botanical Blueprints, circa 1843

Botanical Blueprints, circa 1843

Anna Atkins, pioneering female photographer, revolutionized scientific illustration using a newly invented photographic technique.

Slideshows

Cyan Wonders

Cyan Wonders

In 1842, Anna Atkins, a 43-year-old amateur botanist from Kent, England, began experimenting with a brand-new photographic process called cyanotype or blue-print. 

The View From Above

The View From Above

Satellite imagery is giving biologists a whole new perspective on the phenomena they study.

Contributors

Contributors

Contributors

Meet some of the people featured in the February 2012 issue of The Scientist.

Infographics

Calcium and the Pancreas

Calcium and the Pancreas

Calcium and the Pancreas

Normal pancreatic function depends on the precise flow of calcium within and into the acinar cells of the organ. 
How Autophagy Works

How Autophagy Works

How Autophagy Works

There are five steps of autophagosome biogenesis: induction, expansion, vesicle completion, fusion, and cargo degradation. 

Capsule Reviews

Capsule Reviews

Capsule Reviews

Neurogastronomy, Why Calories Count, The Kitchen as Laboratory, Fear of Food

Videos

Swarming Mongolia

Swarming Mongolia

For the past decade and a half, a crew of about 20 entomologists, water ecologists, and other specialists converges on the shorelines of Mongolia’s lakes, rivers, and streams, just when swarms of aquatic insects do the same.