May 2005

As scientists at the National Institutes of Health, we share the belief of director Elias Zerhouni and others, including Congress and the US public, that any financial conflict of interest at the agency is unacceptable and should be absolutely prohibited by regulations.

If you could teach the world one thing about science, what would it be?

It's been hard to miss the recent antagonism between elements in the religious and scientific communities over issues such as evolution and the ethics of embryonic stem cell research.

A touch of acrimony is infused into many diplomatic relationships between the United States and European nations.

An ancient scourge, tuberculosis has made a comeback in recent years.

Type 1 diabetes, rheumatoid arthritis, and Crohn disease seem clinically diverse, but they arise from acommon problem: poor discrimination between self and nonself.

These papers were selected from multiple disciplines from the Faculty of 1000, a Web-based literature awareness tool http://www.facultyof1000.com.S.G. Tringe et al., "Comparative metagenomics of microbial communities," Science, 308:554–7, April 22, 2005.This important paper provides the first comparative analysis of both phylogenetic and functional diversity of entire microbial communities. The communities considered include those associated with farm soils, deep-sea whale carcasses, the S

In the estimated 5 million years since humans and chimpanzees began diverging, they've acquired major anatomical and cognitive differences.

© 2005 Center for Development BiologyResearchers at the University of Utah are among the first to use large-scale genetics to study the planarian Schmidtea mediterranea, which contains a genome thought to contain insight into adult stem cell pluripotency and tissue regeneration.1Because the organism does not reproduce sexually, it cannot be studied using traditional genetic techniques. But by using bacterial-fed RNA interference against 1065 planarian genes, the study "effectively makes an

It's been a busy year for the microfluidics industry.

I slipped into bioinformatics through the back door.

Visualizing gene expression in living animals, at high spatial resolution and in real time, has been a long-held goal in molecular research.

The same technology that reveals to expectant parents the sex of their developing fetus is now being used for noninvasive, real-time imaging of small, live animals such as mice, rats, chick embryos, and zebrafish.

Since their introduction as a life science tool 15 years ago, surface plasmon resonance (SPR) systems have offered highly sensitive, label-free, real-time detection of molecular interactions.

Johnson began airing new ads for its birth control patch, and viewers may have noticed that the message was significantly more sobering than in past ads.

Johnson, Amgen, Schering-Plough, Bristol-Myers Squibb, and Abbott in an attempt to get the firms to stop using five common animal tests.

In July 2004, 12 drug manufacturers in China successfully challenged Pfizer's Viagra patent, in effect gaining the ability to make sildenafil citrate-containing drugs with impunity.

Zhang Zhihong, a biophysicist at Fudan University in China, receives millions in grants from China's state-run science institutions for his research into the biochemistry of cell membranes and type 2 diabetes.

One of Germany's 16 states, Sachsen-Anhalt, filed a lawsuit in April against a national regulation governing genetically modified (GM) crops.

A US Supreme Court case is dividing the life sciences industry, essentially pitting drug developers against the research tool industry.

If you were a small business owner looking for a loan, you'd expect financial and perhaps accounting advice from your banker.

If you've ever had doubts about the power of advertising, take a look at a recent study appearing in the Journal of American Medical Association.1 Richard Kravitz, from the University of California, Davis, and colleagues found that when "standardized patient" actors portraying depression visited doctors and asked for Paxil, 27% of them walked out with a prescription for the drug, compared to just 3% of patients who described the same symptoms but did not ask for Paxil. That finding should be con

was in graduate school when he was bitten by the programming bug.

while it is true that a number of patents are involved in the technology necessary for the creation of Golden Rice, there is a general public perception that intellectual property (IP) issues have been a main reason for the delay in the introduction of Golden Rice to countries that badly need this technology.

please, spare us the sociological/political nonsense.

I feel obliged to clear up any possible misunderstandings and allay the concerns of protein researchers currently using or planning to use Ni-NTA for purification of His-tagged proteins.

I certainly agree that efforts should be made to minimize fungal contamination at security checkpoints.