Molecular Biology
Molecular Biology
L.-H. Tsai, E. Harlow, M. Meyerson, "Isolation of the human cdk2 gene that encodes the cyclin A- and adenovirus E1A-associated p33 kinase," Nature, 353:174-7, 1991. Li-Huei Tsai (Massachusetts General Hospital Cancer Center, Charlestown, Mass.): "Regulation of the onset of cellular DNA synthesis appears to be an important mechanism for small DNA tumor viruses to immortalize cells. Both the retinoblastoma gene product (pRB) and cyclin A, two of the adenovirus E1A targeted cellular proteins, hav