Monkeys Develop Protective Antibodies to SARS-CoV-2

A small study of macaques finds they don’t develop a coronavirus infection the second time they are exposed, supporting the idea of using plasma from recovered patients as a treatment for COVID-19.

Written byKatarina Zimmer
| 5 min read
coronavirus covid-19 sars-cov-2 antibodies plasma therapy b cells monkey macaques

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Whether people develop immunity to SARS-CoV-2 after being infected once is a pressing question for policymakers, public health professionals, and everyone affected by the spreading COVID-19 pandemic. It’s of particular interest to several research groups and companies currently developing plasma therapies, whereby antibody-containing blood plasma is extracted from recovered patients and administered to patients with severe cases to help them fight off the infection.

Now, a study in monkeys provides some clues. Three rhesus macaques did not develop a second infection after recovering from a first exposure to the coronavirus and being reexposed to SARS-CoV-2, suggesting that primates are capable of developing at least some short-term immunity to the pathogen. The research, posted as a preprint to bioRxiv March 14, has yet to undergo peer review. To the authors, the results indicate that reports of some COVID-19 survivors being “re-infected” a second time can be explained ...

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Meet the Author

  • katya katarina zimmer

    After a year teaching an algorithm to differentiate between the echolocation calls of different bat species, Katarina decided she was simply too greedy to focus on one field of science and wanted to write about all of them. Following an internship with The Scientist in 2017, she’s been happily freelancing for a number of publications, covering everything from climate change to oncology. Katarina is a news correspondent for The Scientist and contributes occasional features to the magazine. Find her on Twitter @katarinazimmer and read her work on her website.

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