A germinal center inside a lymph node
Slow Vaccine Delivery May Maximize Immune Response
A vaccine strategy involving formulation changes, an initial escalating dose, and a longer wait for booster immunization results in more-effective antibody production against HIV in rhesus monkeys, a study finds.
Slow Vaccine Delivery May Maximize Immune Response
Slow Vaccine Delivery May Maximize Immune Response

A vaccine strategy involving formulation changes, an initial escalating dose, and a longer wait for booster immunization results in more-effective antibody production against HIV in rhesus monkeys, a study finds.

A vaccine strategy involving formulation changes, an initial escalating dose, and a longer wait for booster immunization results in more-effective antibody production against HIV in rhesus monkeys, a study finds.

antibodies
A translucent illustration of the BA.2.75 subvariant of SARS-CoV-2 against a black background
Experts Mixed on Risk of “Centaurus” Omicron Subvariant
Dan Robitzski | Aug 15, 2022
BA.2.75 is spreading rampantly in India and has so far reached at least 20 other countries, but it doesn’t seem to be outcompeting other Omicron SARS-CoV-2 subvariants.
Four glass vials sit on a reflective tabletop next to a syringe. Each is labeled as a subsequent dose in a four-dose series of COVID-19 vaccines.
What We Know About Getting a Second Booster Shot of COVID-19 Vaccines
Dan Robitzski | Aug 11, 2022
Studies show that a fourth mRNA vaccine dose offers the elderly and other high-risk groups strong protection against hospitalization and death from COVID-19, but experts say benefits for other populations may be more limited.
An immunoglobulin, also known as an antibody, floating in solution.
Shining a Light on Mass Photometry
The Scientist Creative Services Team and Refeyn
Mass photometry is an interferometric scattering-based technique offering researchers unprecedented characterization of biomolecular complexes and oligomerization in physiologically-relevant situations.
Man in lab coat looking at the camera and smiling
Can Taking a Test Now Tell You if You’ve Already Had COVID-19?
Natalia Mesa | Aug 8, 2022
The Scientist asks Brigham and Women’s Hospital infectious disease specialist Lindsey Baden about testing for prior infections.
illustration of inside of gut with floating bacteria
Finding Could Pave the Way to New, Targeted Antibody Treatments
Natalia Mesa | Jul 8, 2022
IgA antibodies appear to bind to specific species of commensal gut bacteria in mice, according to a study.
Raising the Bar for Biomarkers and Early Diagnostics in Neurodegenerative Disease
Raising the Bar for Biomarkers and Early Diagnostics in Neurodegenerative Disease
Fortis Life Sciences
Identifying novel biomarkers of Parkinson’s disease enables early diagnosis and treatment monitoring.
Vaccine illustration 
Infographic: Inducing Active Immunity Against Opioid Overdose
Tori Rodriguez | Jun 13, 2022
How scientists aim to induce an immune response against addictive drugs
Illustration of a syringe with a person falling out of a bottle of pills
Opioid Vaccines as a Tool to Stem Overdose Deaths
Tori Rodriguez | Jun 13, 2022
Researchers are turning to the immune system for help in treating addiction and preventing overdose.
Optimizing Reproducibility in Flow Cytometry
Beckman Coulter Life Sciences
Explore real solutions for single cell research.
blue gloved hand putting vial of blood into centrifuge machine
Studies Identify Risk Factors for Long COVID
Natalia Mesa | Jan 26, 2022
Two recent papers provide insight into possible risk factors for developing the chronic condition, including autoantibodies and diabetes.
a blood bag partially full of yellow liquid
Convalescent Plasma for COVID-19 Cuts Hospitalizations: Preprint
Shawna Williams | Dec 21, 2021
Unlike studies of antibody-rich transfusions in hospitalized patients, which overall have not found clear benefits, a new randomized trial finds that early convalescent plasma treatment cuts hospitalizations in half.
iStock
The Scientist Speaks - To Conserve and Protect: The Quest for Universal Vaccines
Niki Spahich, PhD
Patrick Wilson discusses the challenges in designing universal vaccines and his work developing one for influenza.
orange and blue cell image
Woman’s Body Appears to Rid Itself of HIV
Chloe Tenn | Nov 18, 2021
Researchers report what appears to be the second case of a person’s immune system clearing the virus on its own.
illustration of people of different genders and races
Does Biological Sex Influence COVID-19 Outcomes?
Annie Melchor | Nov 2, 2021
It’s unclear whether differing odds of dying between men and women reflect inherent differences between male and female immune systems or differences rooted in gender norms.
chipcytometry-tissue
Revolutionizing Cellular Phenotyping with Multiplex Tissue Imaging
The Scientist Creative Services Team and Canopy Biosciences
Highly multiplexed tissue immunohistochemistry combined with an automated, high resolution imaging pipeline resolves unlimited protein targets in intact tissue.  
illustration of a coronavirus and antibodies
When the Immune Response Makes COVID-19 Worse
Alejandra Manjarrez | Sep 27, 2021
If the immune system makes mistakes—reacting late or getting the target wrong—it can amplify the damage wrought by SARS-CoV-2.
moderna and pfizer vaccine vials
Moderna vs. Pfizer: Is There a “Best” mRNA Vaccine?
Alejandra Manjarrez | Sep 24, 2021
Both of the mRNA vaccines available in the US are highly effective against severe COVID-19, but recent studies suggest that Moderna’s elicits a stronger immune response and might be better at preventing breakthrough infections.  
An Improved Way to Detect CAR T Cells and SARS-CoV-2-Binding Cells
Technique Talk: An Improved Way to Detect CAR T Cells and SARS-CoV-2-Binding Cells
The Scientist Creative Services Team and Bio-Techne
Jody Bonnevier will discuss the advantages of Fluorokines™ for detecting and investigating CAR T cells and other key drivers of the immune system.
Updated Mar 8
A healthcare worker holds up three syringes with clear medicine
To Booster or Not: Scientists and Regulators Debate
Jef Akst | Sep 16, 2021
President Biden’s planned rollout of additional COVID-19 vaccine doses is set to begin next week, but questions remain about who should get them.