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Explore How Adaptive Immune Receptor Repertoire Profiling Characterizes Immune Cells
Revealing Immune Responses with Adaptive Immune Receptor Repertoire Profiling
Immune receptor repertoire profiling is an important analytic tool for disease research in many areas, including cancer, cell and organ transplantation, autoimmunity, and infectious disease. 
Revealing Immune Responses with Adaptive Immune Receptor Repertoire Profiling
Revealing Immune Responses with Adaptive Immune Receptor Repertoire Profiling

Immune receptor repertoire profiling is an important analytic tool for disease research in many areas, including cancer, cell and organ transplantation, autoimmunity, and infectious disease. 

Immune receptor repertoire profiling is an important analytic tool for disease research in many areas, including cancer, cell and organ transplantation, autoimmunity, and infectious disease. 

B cell

Microscopy image of the cnidarian <em>Hydractinia symbiolongicarpus&nbsp;</em>with cell nuclei stained blue and oocytes stained yellow
Ancient Immunoglobulin Genes Help Cnidarians Decide to Fight or Fuse
Sophie Fessl, PhD | Oct 11, 2022 | 4 min read
Immunoglobulin genes might have evolved much earlier than previously expected, perhaps even in the common ancestor of Cnidarians and Bilateria, a study suggests.
stained microscope image of a germinal center inside a lymph node
Booster Is Best in the Same Limb as Initial Vaccine: Mouse Study
Alejandra Manjarrez, PhD | May 6, 2022 | 4 min read
Compared to mice who got the doses in separate limbs, animals receiving flu shots in the same paw for both a first and second dose had better-trained memory B cells that bound tighter to the vaccine antigen.
Building Broader B Cell Diversity for Better Monoclonal Antibody Discovery<br ><br>
Building Broader B Cell Diversity for Better Monoclonal Antibody Discovery
The Scientist Staff | 1 min read
In this webinar, Vincent Pai will discuss how the latest automated single B cell functional screening technology helps researchers meet the demands for new monoclonal antibody candidates.
chemical visualization of a G-quadruplex
Strange DNA Structures Linked to Cancer
Sophie Fessl, PhD | Jan 19, 2022 | 3 min read
A study reveals a connection between the loss of enzymes responsible for removing methyl groups from DNA, nucleic acid knots, and cancer development in mice.
Illustration of the BCG vaccine and resulting immune response
Infographic: TB Vaccines in the Pipeline Take Varied Approaches
Anthony King | Jul 1, 2021 | 3 min read
More than a dozen vaccines for tuberculosis are currently being tested in clinical trials. Some use whole bacteria as BCG does, while others deliver protein subunits or genetic material carried by viral vectors.  
Beyond Cytotoxicity: The Importance of T Cell Memory<br ><br>
Beyond Cytotoxicity: The Importance of T Cell Memory
The Scientist | 1 min read
In this webinar, Grégoire Lauvau and Marcus Buggert will discuss the function and role of memory T cells in health and disease.
False-colored micrograph of Mycobacterium tuberculosis
Tuberculosis: The Forgotten Pandemic
Anthony King | Jul 1, 2021 | 10+ min read
This month marks the 100-year anniversary of BCG, still the only approved vaccine against the lethal pathogen. But there are new vaccines for this wily foe on the horizon.
lymph node germinal center antibody covid-19 sars-cov-2 pandemic coronavirus plasmablast b cell pfizer vaccine immunity
Pfizer Vaccine Induces Immune Structures Key to Lasting Immunity
Katarina Zimmer | Mar 25, 2021 | 6 min read
In the armpit lymph nodes of people who had received the mRNA vaccine against SARS-CoV-2, researchers found germinal centers needed to generate long-lived antibody-making cells.
Cancer Vaccines: A Dose of Prevention
Cancer Vaccines: A Dose of Prevention
The Scientist | 1 min read
Discover the latest progress behind therapeutic vaccines that boost the immune system’s cancer-killing abilities.
cancer blood hematologic leukemia solid tumor covid-19 sars-cov-2 coronavirus pandemic mortality t cell b cd8+ cd4+ immunology chemotherapy
COVID-19 More Deadly with Blood than Solid Cancer: Study
Marcus A. Banks | Feb 16, 2021 | 4 min read
Death rates among blood cancer patients who contract COVID-19 are higher than for those with other cancers, pointing to impaired immunity that makes it hard to overcome the virus.
Immunity to SARS-CoV-2 Lasts at Least Six Months, Data Show
Ashley Yeager | Nov 23, 2020 | 4 min read
Half a year after infection, people who had recovered from COVID-19 had robust antibodies, along with traces of the virus in their gut, which may drive long-lasting immunity.
LabTalk Podcast - Predicting the Immune Response with Single-Cell Analysis: Autoimmunity, Vaccination, and COVID-19
The Scientist and 10x Genomics | 1 min read
Researchers identify signatures that predict how a person will respond to an immune system stimulus.
Common Cold Coronaviruses Tied to Less Severe COVID-19 Cases
Anthony King | Nov 11, 2020 | 5 min read
Outcomes in COVID-19 patients may be better in those recently infected with endemic coronaviruses. 
germinal centers antibody antibodies covid-19 sars-cov-2 pandemic coronavirus immunity
Some COVID-19 Patients Lack Key Structures for Antibody Creation
Katarina Zimmer | Aug 25, 2020 | 5 min read
An absence of germinal centers—which arise during infections to produce long-lived antibody-generating cells—might explain rapidly waning antibody levels in the disease.
Investigating the Immune Response Using Advanced Flow Cytometry
The Scientist | 1 min read
Discover how researchers are using flow cytometry to delve into the inner workings of the immune life cycle!
Regulator of Mysterious Gut Antibodies Identified
Ruth Williams | Jul 31, 2020 | 3 min read
A B-cell receptor critical for the production of a subset of intestinal antibodies has been pinpointed, but the function of those antibodies remains unclear.
t cell b cell covid-19 coronavirus pandemic sars-cov-2 immune response innate immunity adaptive immunity antibodies antibody cd8+
The Search for Immune Responses that Stop COVID-19
Chris Baraniuk | Jul 24, 2020 | 5 min read
Scientists are examining the role of T cells, which are likely crucial for long-term protection against SARS-CoV-2.
SARS-CoV-2 Antibody Durability
The Scientist | 1 min read
Experts will discuss their research on SARS-CoV-2 antibody persistence and immune memory in recovered COVID-19 patients and the implications for protective immunity.
bcg tuberculosis tb sars-cov-2 covid-19 coronavirus pandemic vaccine nonspecific effects trained immunity innate immune system response
An Old TB Vaccine Finds New Life in Coronavirus Trials
Anthony King | May 4, 2020 | 8 min read
Studies are underway to test whether giving a shot of BCG vaccine could protect doctors and nurses against COVID-19.
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