Nanoscale Defenses

Coating hospital surfaces, surgical equipment, patient implants, and water-delivery systems with nanoscale patterns and particles could curb the rise of hospital-acquired infections.

Written byEdward D. Marks and Steven Smith
| 10 min read

Register for free to listen to this article
Listen with Speechify
0:00
10:00
Share

FROM TOP (LEFT TO RIGHT): © Science Source/CDC/Phanie; © Science Source/Gary D. Gaugler; © Science Source/Eye of Science; Mary Nora Dickson; © Science Source/David Scharf

Picture a hospital room: white walls, stainless steel IV poles and bedrails, scratchy bedsheets. For more than 100 years, this has been the standard hospital environment, and for most of that time, isolating patients in hygienic rooms, instead of en masse in group clinics or sanatoria, has helped curb the spread of infections that once killed nearly half of soldiers on the battlefield and more than a third of newborn infants. But with the recent rise in antibiotic-resistant pathogens, this standard is no longer sustainable. In 2011, the most recent year data are available from the US Centers for Disease Control and Prevention (CDC), some 720,000 patients acquired an infection while being treated in a health care facility; more than 75,000 of those people died.

“Imagine one full jumbo jet crashed each day, killing everyone on board,” says Michael Schmidt, vice chairman of microbiology and immunology at the Medical University of South Carolina (MUSC). “This is precisely the number of people that die each day in the U.S. from a hospital-associated infection.”

We can turn almost any material into one that reduces bacterial adhesion and growth, all by imple­menting nanoscale features.—Thomas Webster,
Northeastern Univer­sity

In the face of such hospital-acquired, or nosocomial, infections, and the impossibility of developing effective antibiotics quickly enough, researchers are looking to update that white-walled hospital room. The stainless steel IV ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to digital editions of The Scientist, as well as TS Digest, feature stories, more than 35 years of archives, and much more!
Already a member? Login Here
Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue
Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

Unchained Labs
Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

illumina
Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

Abstract illustration of spheres with multiple layers, representing endoderm, ectoderm, and mesoderm derived organoids

Organoid Origins and How to Grow Them

Thermo Fisher Logo

Products

Brandtech Logo

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

Biotium Logo

Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Fisher Logo
Abstract background with red and blue laser lights

VANTAstar Flexible microplate reader with simplified workflows

BMG LABTECH