Newly Discovered Virus Has Multi-Part Genome

A “multicomponent” virus isolated from mosquitoes infects in stages and reassembles once the pieces are inside the host.


Register for free to listen to this article
Listen with Speechify
0:00
1:00
Share

A mosquito from the genus Culex, which harbors Guaico Culex virusWIKIMEDIA, ALAN R. WALKERResearchers have discovered a new, “multicomponent” virus that infects mosquitoes: one of the first times that such a virus isolated from an animal. The new virus—named the Guaico Culex virus (GCXV) by the scientists who described it in a Cell Host & Microbe paper published this week (August 25)—has a genome that comes in five pieces, each of which is separately packaged. In order for a mosquito to be infected by the virus, at least four of these segments must invade the host.

“It’s the most bizarre thing,” Edward Holmes, a virologist at the University of Sydney, told NPR’s Goats and Soda. “If you compare it to the human body, it’s like a person would have their legs, trunk and arms all in different places,” added Holmes, who was not involved with the study. “Then all the pieces come together in some way to work as one single virus. I don’t think anything else in nature moves this way.”

Viruses with multicomponent genomes commonly infect plants and fungi, but they are far rarer in animals.

The study that discovered and described GCXV was part of a broader effort to better understand mosquito-borne viruses. The research team reported finding a variant of the new virus in a red colobus ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Keywords

Share
Image of a woman in a microbiology lab whose hair is caught on fire from a Bunsen burner.
April 1, 2025, Issue 1

Bunsen Burners and Bad Hair Days

Lab safety rules dictate that one must tie back long hair. Rosemarie Hansen learned the hard way when an open flame turned her locks into a lesson.

View this Issue
Conceptual image of biochemical laboratory sample preparation showing glassware and chemical formulas in the foreground and a scientist holding a pipette in the background.

Taking the Guesswork Out of Quality Control Standards

sartorius logo
An illustration of PFAS bubbles in front of a blue sky with clouds.

PFAS: The Forever Chemicals

sartorius logo
Unlocking the Unattainable in Gene Construction

Unlocking the Unattainable in Gene Construction

dna-script-primarylogo-digital
Concept illustration of acoustic waves and ripples.

Comparing Analytical Solutions for High-Throughput Drug Discovery

sciex

Products

Green Cooling

Thermo Scientific™ Centrifuges with GreenCool Technology

Thermo Fisher Logo
Singleron Avatar

Singleron Biotechnologies and Hamilton Bonaduz AG Announce the Launch of Tensor to Advance Single Cell Sequencing Automation

Zymo Research Logo

Zymo Research Launches Research Grant to Empower Mapping the RNome

Magid Haddouchi, PhD, CCO

Cytosurge Appoints Magid Haddouchi as Chief Commercial Officer