B.P. Tu et al., ?Logic of the yeast metabolic cycle: temporal compartmentalization of cellular processes,? Science, 310:1152?8, Nov. 18, 2005.
Cells grown in continuous and nutrient-limited conditions exhibit periodic metabolic cycles accompanied by a synchronized expression of most of their genes in three consecutive waves. This temporal compartmentalization might optimize key metabolic and cell-cycle processes and could be the origin of circadian and ultradian oscillators.
Jürg Bähler?The Wellcome Trust Sanger Institute, United Kingdom
R.C. Albertson et al., ?Integration and evolution of the cichlid mandible: The molecular basis of alternate feeding strategies,? Proc Natl Acad Sci, 102:16287?92, Nov. 8, 2005.?
This paper combines genetic and developmental data to implicate bmp4 (bone morphogenetic protein 4) as a key locus in the evolution of jaw morphology in cichlid fish. ? It suggests that bmp4 might be of general importance in the evolution of vertebrate head diversity.
Sebastian Shimeld?University of Oxford, United Kingdom
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