People International Society Honors Two Researchers For Breakthrough Work In Cancer Diagnostics; Roche Institute Recognizes Scientist for Protein Transport Studies

David M. Goldenberg, president of the Garden State Cancer Center, a cancer research institution in Newark, N.J., and Jean-Pierre Mach, a professor of biochemistry in the faculty of medicine at Lausanne University, Switzerland--were honored last month with the 1994 Abbott Award. The award was presented at the 22nd meeting of the International Society for Oncodevelopmental Biology (ISOBM), held in Groningen, the Netherlands. ISOBM, cu

Written byNeeraja Sankaran
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ISOBM, currently headquartered in Freiberg, Germany, is an international scholarly society for immunologists and cancer biologists who have an interest in tumor markers. It produces a monthly research journal, Tumor Biology, published by S. Kargers Publishers Inc. of Basel, Switzerland. The annual Abbott Award was established by Abbott Park, Ill.-based Abbott Laboratories five years ago to recognize ISOBM members for their research and service to the society.

Goldenberg and Mach worked independently but along parallel lines to develop a technique for detecting cancers using radioactive antibodies specific for certain molecules--called markers--present on the surface of tumor cells. Goldenberg published the clinical paper that demonstrated the use of the technique (D.M. Goldenberg et al., New England Journal of Medicine, 298:1384-8, 1978), and Mach's group followed closely with a critical evaluation of the technique, demonstrating the specificity of localization of the antibodies (J.P. Mach et al., NEJM, 303:5-10, 1980).

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