Phenotypic CRISPR Screening: Looking Beyond Cell Viability To Study Complex Genetic Interactions

Horizon Discovery invites you to join them for an educational webinar.

Event Details:Phenotypic CRISPR Screening: Looking Beyond Cell Viability To Study Complex Genetic Interactions Date(s):

Phenotypic CRISPR Screening: Looking Beyond Cell Viability To Study Complex Genetic Interactions from thescientistllc on Vimeo.

CRISPR screening, whether using knockout, activation, or inhibition approaches, has become an essential tool for drug discovery. A powerful adaptation of CRISPR screening is created by coupling pooled NGS-linked or arrayed screening strategies with phenotypic measurements. By using an advanced combination of techniques, this screening strategy can be targeted to detect genes that drive complex biological responses via biomarker signal readout or a panel of high content parameters. Scientists at Horizon, the sponsor of this LabTools webinar, have developed both FACS-linked and HCA-based strategies for analysis where cellular pathophysiology is uncoupled from cell health, providing much richer and biologically relevant outcomes. In this webinar, we will discuss data obtained and strategies learned from several successful screens and present ongoing work using increasingly relevant cell models, such as T cells and using single cell RNAseq-based ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here
Share
3D illustration of a gold lipid nanoparticle with pink nucleic acid inside of it. Purple and teal spikes stick out from the lipid bilayer representing polyethylene glycol.
February 2025, Issue 1

A Nanoparticle Delivery System for Gene Therapy

A reimagined lipid vehicle for nucleic acids could overcome the limitations of current vectors.

View this Issue
Considerations for Cell-Based Assays in Immuno-Oncology Research

Considerations for Cell-Based Assays in Immuno-Oncology Research

Lonza
An illustration of animal and tree silhouettes.

From Water Bears to Grizzly Bears: Unusual Animal Models

Taconic Biosciences
Sex Differences in Neurological Research

Sex Differences in Neurological Research

bit.bio logo
New Frontiers in Vaccine Development

New Frontiers in Vaccine Development

Sino

Products

Tecan Logo

Tecan introduces Veya: bringing digital, scalable automation to labs worldwide

Explore a Concise Guide to Optimizing Viral Transduction

A Visual Guide to Lentiviral Gene Delivery

Takara Bio
Inventia Life Science

Inventia Life Science Launches RASTRUM™ Allegro to Revolutionize High-Throughput 3D Cell Culture for Drug Discovery and Disease Research

An illustration of differently shaped viruses.

Detecting Novel Viruses Using a Comprehensive Enrichment Panel

Twist Bio