A screen of diploid yeast mutants has identified over a hundred genes involved in the response to ionizing radiation.
Cells must be able to recognize and repair DNA damage if they are to tolerate the effects of radiation. Much of our understanding of mammalian repair mechanisms, and their involvement in cancer, has come from studying yeast. In the Advanced Online Publication issue of
They screened a set of diploid
Many of these are also involved in resistance to other DNA-damaging agents, such as ultraviolet irradiation or genotoxic drugs. Several ...
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A new system that enables researchers to uniquely tag monoclonal antibodies for use in microscopy could help simplify complex imaging studies.
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Discover how single-molecule Fiber-seq is revealing unexpected mechanisms of transcription factor regulation, chromatin accessibility, and essential gene activation at CpG-island promoters.
Explore how emerging biomarker research and ultrasensitive multiplex proteomics are revealing molecular signatures associated with neurodegeneration, inflammation, and disease progression in amyotrophic lateral sclerosis (ALS).
Explore how in vivo CAR-neutrophil engineering and advanced light-sheet imaging are opening new avenues for studying and targeting glioblastoma and other solid tumors.
Explore practical strategies for designing, optimizing, and validating qPCR assays to improve specificity, reproducibility, and confidence across routine and high-throughput gene expression studies.
Automation can help to increase efficiency and reproducibility, but often comes at a significant cost. The ASSIST PLUS pipetting robot streamlines workflows at an affordable price, offering accessible automation with minimal programming requirements.
Corning® Cell Strainers are sterile, easy-to-use devices for rapidly isolating primary cells to consistently obtain a uniform single-cell suspension from tissues. Applications include stem cells and primary cells.
Real time imaging shouldn't outlast your cell surface stain. CellBrite® Steady: cell surface staining kits with fluorescent membrane dye plus enhancer for imaging live cell surface for several hours to days.
Partnership brings Monod Bio’s LuxSit luciferase and NovoBodies to SignalChem Biotech’s custom assay services
