Restoring C-Section Babies’ Microbiota

A small pilot study suggests exposure to maternal vaginal fluids could restore infant microbiota following Cesarean-section delivery.

Written byCatherine Offord
| 3 min read

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WIKIMEDIA, ERNEST FBabies born by Cesarean section (C-section) are not always exposed to bacteria and other microbes present in the birth canals of their mothers, a factor that some studies have linked to potential health risks later in life. Now, researchers have presented preliminary data suggesting that microbial communities could be at least partly restored by swabbing C-section–delivered babies with their mothers’ vaginal fluids immediately after birth. The results appeared today (February 1) in Nature Medicine.

“Despite the small number of subjects, our study shows significant differences in the bacterial communities of C-section infants exposed to the maternal vaginal fluid, whose microbiota is partially restored and more similar to that of vaginally delivered infants,” study coauthor Jose Clemente, an assistant professor at Icahn School of Medicine at Mount Sinai in New York City, told reporters during a press briefing.

Considered medically necessary in just 10 percent to 15 percent of births, C-sections are used to deliver approximately one in three babies born in the U.S., according to the Centers for Disease Control and Prevention. The practice carries considerable risks for mothers, including the possibility of medical complications such as unplanned hysterectomies and ruptured uteruses.

C-sections also pose risks to the infants ...

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Meet the Author

  • After undergraduate research with spiders at the University of Oxford and graduate research with ants at Princeton University, Catherine left arthropods and academia to become a science journalist. She has worked in various guises at The Scientist since 2016. As Senior Editor, she wrote articles for the online and print publications, and edited the magazine’s Notebook, Careers, and Bio Business sections. She reports on subjects ranging from cellular and molecular biology to research misconduct and science policy. Find more of her work at her website.

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