Scanning the Psychedelic Brain

Brain scans reveal the surprising secret of magic mushrooms’ hallucinogenic effect.

ruth williams
| 3 min read

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Psilocybin cubensis mushroomFLICKR, KRISTIE GIANOPULOS

The geometric visuals and vivid imaginings experienced by those tripping on mushrooms are not, as scientists had suspected, the result of increased brain activity, according to a report out today (23 January) in Proceedings of the National Academy of Sciences. Instead, under the influence of psilocybin—the psychedelic component of magic mushrooms—brain activity and connectivity decrease. The reduced connectivity might be what frees people’s minds from normal constraints, the researchers propose.

“It was often thought to be the case that these classic hallucinogens must increase brain function—you know, they expand awareness, expand consciousness—but in fact what we see is decreased activity,” said Roland Griffiths of Johns Hopkins Bayview Medical Center, who was not involved in the study.

“I have to say this was totally unexpected,” said ...

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  • ruth williams

    Ruth Williams

    Ruth is a freelance journalist.
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