Shift Work Early in Life Results in Increased Stroke Severity in Middle Age

Researchers found that shifted sleep/wake cycles in young rats result in increased functional deficits and mortality following stroke later in life.

Written byJennifer Zieba, PhD
| 3 min read
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Our circadian rhythms, or body clocks, are governed by light-dark cycles and play an important role in human health. However, shift work, or working outside of the hours of 7 AM to 6 PM, results in a desynchronization of these rhythms.1 This dysregulation is implicated in multiple human disorders including cancers, metabolic disease, obesity, diabetes, and vascular diseases.2-5 However, existing studies are unable to separate disease risk from other factors such as smoking or socioeconomic status. With remote work becoming the norm, the study of inconsistent sleep-wake schedules and their effect on our health will only become more important.

David Earnest, a professor at the Texas A&M Health Science Center, is interested in circadian rhythms and their effect on the cardiovascular system. “It was really only about 10 or 15 years ago that studies really started to come forward, particularly human epidemiological studies, to show that people doing shift work ...

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  • Jennifer Zieba, PhD headshot

    Jen earned her PhD in human genetics at the University of California, Los Angeles. She is currently a project scientist in the orthopedic surgery department at UCLA where she works on identifying mutations and possible treatments for rare genetic musculoskeletal disorders. Jen enjoys teaching and communicating complex scientific concepts to a wide audience and is a freelance writer for The Scientist's Creative Services Team.

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